Silodosin for Urinary Symptoms in Women with MS
Silodosin for Urinary Symptoms in Female Patients With Multiple Sclerosis
Recruiting
Phase 4
Interventional Study
Multiple Sclerosis
Lower Urinary Track Symptoms
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Female
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 60 (estimated)
- Sponsor
- Atlantic Health System · Other
Who this trial is looking for
This trial is looking for women with multiple sclerosis who have problems with their urinary tract. Participants will take either silodosin or a placebo every day for 8 weeks and visit the clinic to answer questions and undergo tests.
Are You a Good Fit for This Trial?
You may be able to join if
- I am a female.
- I have been diagnosed with multiple sclerosis.
- I am over 18 years old.
- I have moderate to severe urinary symptoms.
- I do not have a urinary tract infection.
You may not be able to join if
- I have taken certain medications for urinary symptoms in the last 6 weeks.
- I have received specific treatments for my bladder in the last 9 months.
- I have kidney problems.
- I have a bladder volume greater than 300.
- I have orthostatic hypotension.
- I am pregnant or breastfeeding.
- I have severe liver problems.
- I have kidney stones causing symptoms.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
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About This Trial
The goal of this clinical trial is to learn if silodosin works to treat lower urinary tract symptoms (LUTS) in female patients with multiple sclerosis (MS). It will also learn about the effect of the drug on voiding parameters. The main questions it aims to answer are:
Does silodosin improve lower urinary tract symptoms based on questionnaires? Does silodosin change Uroflowmetry parameters in fem…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Female patients with a diagnosis of multiple sclerosis
2. Age \> 18
3. Moderate to severe lower urinary tract symptoms as defined by an AUASS score \> 8
4. No UTI
Exclusion Criteria:
1. Treatment with alpha-blocker, B3 agonist, or anticholinergic medication within the last …
Contacts