143 Recruiting Trials

Clinical Trials
for Breast Cancer in New Jersey

143 clinical trials for Breast Cancer are currently recruiting participants at study sites in New Jersey. Study-related care is provided at no cost.

143
Recruiting trials
183
Study sites
55
Cities
62
Industry-sponsored
44
Phase 2
36
Phase 3

Breast Cancer clinical trials in New Jersey: what to expect

Breast cancer trials are sorted first by subtype, because the treatments differ: hormone-receptor-positive, HER2-positive (including the newer HER2-low group) and triple-negative disease each have their own studies. Most recruiting trials test a new drug or combination, including targeted pills, antibody-drug conjugates and immunotherapy, either for metastatic cancer or before and after surgery for early-stage disease. Others study less surgery or radiation, ways to reduce recurrence, and screening for people at higher risk.

In New Jersey, recruiting breast cancer studies are concentrated in Basking Ridge, Middletown, Montvale and New Brunswick, with sites in 51 other cities. 62 of the 143 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who breast cancer trials usually look for

Listings name the subtype, the stage (early or metastatic) and how many treatments you may already have had. Early-stage trials often enroll between diagnosis and surgery, or in the months after surgery; metastatic trials usually enroll when a treatment has stopped working. Some specify menopausal status or a particular mutation (BRCA, PIK3CA, ESR1), which the site can test for. Nearly all require that you are well enough for daily activity and that recent blood work is adequate.

Your receptor status is on your pathology report; the site will confirm it from that report, so you do not need to know it by heart to ask.

What taking part involves

Screening reviews your pathology and scans and adds blood work, sometimes a biopsy. Treatment then runs in cycles, with infusions every two to three weeks or daily pills, and scans every two to three months to check the response. Early-stage trials follow you for years after treatment ends, usually with a visit or call every few months. Study drugs and study-specific tests are free; care you would receive anyway is billed to insurance as usual. Placebo, when used, is added to standard treatment.

Questions worth asking the study team

How the study treatment compares with what your oncologist would otherwise recommend; whether the trial is randomized and what the other arm receives; what happens if the cancer grows or returns; and how visits fit around work and family. Many trials now allow some visits at a local clinic.

Showing 20 of 143 recruiting Breast Cancer trials in New Jersey

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
PHASE3 Anchorage, Alaska +4 sites NCT07062965
This trial is looking for people with HR-positive, HER2-negative advanced breast cancer that has worsened after previous treatment. Participants will receive the study medicine PF-07248144 along with their normal treatment options to see how well they work together.
Recruiting
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
PHASE3 Goodyear, Arizona +4 sites NCT06790693
This trial is looking for adults with a specific type of advanced breast cancer to test a new treatment combo. Participants will receive either the new treatment or a placebo along with standard care.
Recruiting
A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy
PHASE3 Greenbrae, California +4 sites NCT05646862
This trial is looking for people with advanced breast cancer that has specific mutations and has not improved after certain treatments. Participants will compare two treatment combinations to see which is more effective and safe.
Recruiting
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
PHASE3 Daphne, Alabama +4 sites NCT06492616
This trial is looking for women and men with early breast cancer that has a high risk of coming back. Participants will compare the effects of elacestrant with standard treatment after being on another therapy for a while.
Recruiting
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
PHASE3 Birmingham, Alabama +4 sites NCT05879926
This trial is looking for premenopausal women with early-stage breast cancer that is hormone receptor-positive. Participants will receive hormone therapy and may also get chemotherapy to see if it helps them live longer without cancer returning.
Recruiting
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
PHASE3 Phoenix, Arizona +4 sites NCT06072612
This trial is looking for adults with advanced or locally recurrent breast cancer who have run out of treatment options. Participants will receive treatment with the Bria-IMT regimen and a checkpoint inhibitor to see how well it works compared to other standard treatments.
Recruiting
E-Mindfulness Approaches for Living After Breast Cancer
PHASE3 Phoenix, Arizona +4 sites NCT06748222
This trial is looking for younger women who have survived breast cancer and are experiencing depression. Participants will try two different mindfulness programs, one led by an instructor via Zoom and the other through a mobile app.
Recruiting
Trastuzumab Deruxtecan (T-DXd) in Patients Who Have Hormone Receptor-negative and Hormone Receptor-positive HER2-low or HER2 IHC 0 Metastatic Breast Cancer
PHASE3 Summit, New Jersey +4 sites NCT05950945
This trial is looking for people with certain types of breast cancer to see how a treatment called trastuzumab deruxtecan works. Participants need to provide tissue samples and meet specific health criteria.
Recruiting
A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer
PHASE1 Huntsville, Alabama +4 sites NCT07100106
This trial is looking for people with advanced breast cancer that is hormone receptor positive and HER2 negative. Participants will receive GDC-4198 by itself or with another drug, Giredestrant, to see how well it works and compare it to another treatment option.
Recruiting
To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With Breast Cancer
PHASE2 East Brunswick, New Jersey +4 sites NCT07368998
This trial is looking for adults with a specific type of breast cancer who have had treatment before. Participants will take a combination of two medications and help researchers understand their effects.
Recruiting
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
PHASE2 Long Beach, California +4 sites NCT07102381
This trial is looking for people with early-stage HER2-positive breast cancer to see if zanidatamab combined with chemotherapy is safe and effective. Participants will need to undergo surgery after the treatment.
Recruiting
A Study of Multiparametric MRI and pHLIP® ICG in Breast Cancer Imaging During Surgery
PHASE1 Montvale, New Jersey +1 sites NCT05130801
This trial is looking for adults with a confirmed diagnosis of breast cancer. Participants will receive advanced imaging before and during surgery to better see and remove tumors.
Recruiting
A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer
PHASE2 Basking Ridge, New Jersey +4 sites NCT05570253
This trial is looking for people with advanced breast cancer that has spread and certain metabolic issues. Participants will receive a combination of the study drug SDX-7320 and the chemotherapy drug eribulin, and researchers will assess how effective this treatment is compared to eribulin alone.
Recruiting
Shortening Adjuvant Photon and Proton Irradiation (SAPPHIRe-II): A 4 Cohort, Randomized, Phase II Multi-center Trial Evaluating Shorter Schedules of Adjuvant Regional Nodal Irradiation Among Women and Men With Node-positive and High-risk Node-negative Invasive Breast Cancer
PHASE2 Voorhees Township, New Jersey +4 sites NCT07076485
This trial is looking for individuals with certain types of breast cancer who have had surgery. Participants will receive shorter schedules of special radiation treatment to see how it affects their cancer risk.
Recruiting
Study of Aerobic Training for People Receiving Treatment for Breast Cancer
PHASE2 Basking Ridge, New Jersey +4 sites NCT05716893
This trial is looking for women aged 18 and older who have been diagnosed with primary breast cancer. Participants will compare two types of aerobic exercise programs: a fixed amount of walking versus an adjusted program based on their response to exercise.
Recruiting
A Study of Romosozumab in People With Breast Cancer and Osteoporosis
PHASE2 Basking Ridge, New Jersey +4 sites NCT07776613
This trial is looking for people with metastatic breast cancer that has spread to the bones and osteoporosis. Participants will receive romosozumab to see if it helps with bone health and to check its safety.
Recruiting
Recruiting
A Study of Blood Pressure Control During Cancer Treatment
PHASE2 Basking Ridge, New Jersey +4 sites NCT06023576
This trial is looking for women with breast cancer who need help controlling high blood pressure during their treatment. Participants will follow a specific plan for managing their blood pressure to see if it's more effective than standard methods.
Recruiting
A Study of Radiation Therapy With Pembrolizumab and Olaparib or Other Radiosensitizers in Women Who Have Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancer
PHASE2 Basking Ridge, New Jersey +4 sites NCT04683679
This trial is looking for women with specific types of breast cancer to see if combining pembrolizumab with radiation therapy is a safe and effective treatment. Participants will receive treatment and can help researchers understand its effectiveness compared to standard radiation therapy alone.
Recruiting
A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer
PHASE2 Tucson, Arizona +4 sites NCT06568692
This trial is looking for patients with advanced breast cancer to test a new treatment combination. Participants will receive either PCS6422 with capecitabine or capecitabine alone.
Recruiting

Where the Breast Cancer studies are in New Jersey

  • Rutgers Cancer Institute of New Jersey, New Brunswick18 trials
  • Memorial Sloan Kettering Bergen (Limited Protocol Activities), Montvale17 trials
  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities), Middletown15 trials
  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge14 trials
  • Memorial Sloan Kettering Bergen (All Protocol Activities), Montvale11 trials
  • Memorial Sloan Kettering Monmouth (All Protocol Activities), Middletown9 trials

Counts are recruiting studies listing at least one site in New Jersey, from ClinicalTrials.gov, refreshed every two days.

Breast Cancer clinical trials in New Jersey: common questions

How many Breast Cancer clinical trials are recruiting in New Jersey?
TrialFinder currently lists 143 recruiting Breast Cancer clinical trials with study sites in New Jersey. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Breast Cancer clinical trials located in New Jersey?
Study sites for the Breast Cancer trials listed on this page include Summit, East Brunswick, Montvale, Basking Ridge, Voorhees Township. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Breast Cancer clinical trial in New Jersey?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Breast Cancer trials in New Jersey also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Breast Cancer clinical trial in New Jersey?
Each study sets its own criteria based on age, Breast Cancer diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need to know my receptor status to join a breast cancer trial?
It helps, because trials are organized by subtype, but the study site reads it from your pathology report. If a trial needs a test you have not had, such as HER2-low or a BRCA result, the site arranges it.
Are there trials for early-stage breast cancer?
Yes. Early-stage trials enroll before surgery, after surgery, or during the years of hormone therapy that follow, and test ways to lower the chance the cancer returns. The listing says which window it enrolls in.
Will a trial replace the treatment my oncologist planned?
Sometimes it is the plan, with a new drug added or compared; sometimes it is an alternative to discuss. Bring the trial page to your oncologist, who can refer you to the site or advise on timing.
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