24 Recruiting Trials

Clinical Trials
for Breast Cancer in West Virginia

24 clinical trials for Breast Cancer are currently recruiting participants at study sites in West Virginia. Study-related care is provided at no cost.

24
Recruiting trials
22
Study sites
10
Cities
12
Industry-sponsored
4
Phase 2
11
Phase 3

Breast Cancer clinical trials in West Virginia: what to expect

Breast cancer trials are sorted first by subtype, because the treatments differ: hormone-receptor-positive, HER2-positive (including the newer HER2-low group) and triple-negative disease each have their own studies. Most recruiting trials test a new drug or combination, including targeted pills, antibody-drug conjugates and immunotherapy, either for metastatic cancer or before and after surgery for early-stage disease. Others study less surgery or radiation, ways to reduce recurrence, and screening for people at higher risk.

In West Virginia, recruiting breast cancer studies are concentrated in Morgantown, Charleston, Huntington and Parkersburg, with sites in 6 other cities. 12 of the 24 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who breast cancer trials usually look for

Listings name the subtype, the stage (early or metastatic) and how many treatments you may already have had. Early-stage trials often enroll between diagnosis and surgery, or in the months after surgery; metastatic trials usually enroll when a treatment has stopped working. Some specify menopausal status or a particular mutation (BRCA, PIK3CA, ESR1), which the site can test for. Nearly all require that you are well enough for daily activity and that recent blood work is adequate.

Your receptor status is on your pathology report; the site will confirm it from that report, so you do not need to know it by heart to ask.

What taking part involves

Screening reviews your pathology and scans and adds blood work, sometimes a biopsy. Treatment then runs in cycles, with infusions every two to three weeks or daily pills, and scans every two to three months to check the response. Early-stage trials follow you for years after treatment ends, usually with a visit or call every few months. Study drugs and study-specific tests are free; care you would receive anyway is billed to insurance as usual. Placebo, when used, is added to standard treatment.

Questions worth asking the study team

How the study treatment compares with what your oncologist would otherwise recommend; whether the trial is randomized and what the other arm receives; what happens if the cancer grows or returns; and how visits fit around work and family. Many trials now allow some visits at a local clinic.

Showing 20 of 24 recruiting Breast Cancer trials in West Virginia

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
PHASE3 Birmingham, Alabama +4 sites NCT05879926
This trial is looking for premenopausal women with early-stage breast cancer that is hormone receptor-positive. Participants will receive hormone therapy and may also get chemotherapy to see if it helps them live longer without cancer returning.
Recruiting
A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer
PHASE2 Morgantown, West Virginia +4 sites NCT07054190
This trial is looking for people with specific types of breast cancer who have not yet received treatment. Participants will take a combination of new therapies and may need to have surgery afterward.
Recruiting
Pioglitazone Therapy Targeting Fatigue in Breast Cancer
PHASE2 Morgantown, West Virginia NCT05013255
This trial is looking for women with certain types of breast cancer who are experiencing muscle fatigue. Participants will take a medication called pioglitazone daily to see if it helps improve their fatigue before surgery.
Recruiting
EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)
N/A Anchorage, Alaska +4 sites NCT06401421
This trial is looking for adults with early, high-risk breast cancer who plan to start chemotherapy. Participants will provide blood and tissue samples for research and will be followed for up to 5.5 years.
Recruiting
A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy
PHASE3 Birmingham, Alabama +4 sites NCT05774951
This trial is looking for people with early breast cancer who have completed at least 2 years of standard treatment. Participants will receive camizestrant to see if it helps improve their outcomes compared to standard therapy.
Recruiting
Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer
PHASE3 Gilbert, Arizona +4 sites NCT06380751
This trial is looking for adults with certain types of advanced breast cancer. Participants will take either a combination of drugs or a standard treatment chosen by their doctor to see which works better.
Recruiting
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
PHASE3 Birmingham, Alabama +4 sites NCT04852887
This trial is looking for women with early-stage hormone-sensitive breast cancer who are interested in taking part in a study on surgery and hormone therapy without radiation. Participants will need to meet specific health criteria to join.
Recruiting
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
PHASE3 Birmingham, Alabama +4 sites NCT06058377
This trial is looking for women with hormone receptor positive, HER2 negative stage II-III breast cancer. Participants will receive standard chemotherapy along with an immunotherapy drug called durvalumab to see if it helps prevent cancer from coming back.
Recruiting
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
PHASE3 Birmingham, Alabama +4 sites NCT05633654
This trial is looking for adults with triple negative breast cancer that remains after surgery and treatment. Participants will receive an experimental treatment combining two medications after recovery from surgery.
Recruiting
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
PHASE3 Phoenix, Arizona +4 sites NCT06876714
This trial is looking for adults with HER2-positive breast cancer who have no residual invasive disease after chemotherapy. Participants will receive either 6 or 12 months of HER2-targeted medications to see which duration works best.
Recruiting
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
PHASE3 Birmingham, Alabama +4 sites NCT05812807
This trial is looking for people with early-stage triple-negative breast cancer who had no cancer left after previous treatments. Participants will either continue receiving pembrolizumab or just be monitored after surgery to see which approach works better to prevent cancer from coming back.
Recruiting
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
PHASE3 Birmingham, Alabama +4 sites NCT05929768
This trial is looking for women with early-stage triple negative breast cancer. Participants will receive a shorter treatment plan involving chemotherapy and immunotherapy without a certain type of drug called anthracyclines.
Recruiting
Lifting More Than Weights: Resistance Exercise Program Across Socioeconomic Groups for Cancer-Related Fatigue Management
NA Morgantown, West Virginia NCT06960720
This trial is looking for women who have been diagnosed with breast cancer and are experiencing fatigue. Participants will follow a guided strength training program for three months and keep track of their progress.
Recruiting
A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors
PHASE1 Duarte, California +4 sites NCT07029399
This trial is looking for adults with advanced solid tumors, especially certain types of breast cancer that are hard to treat. Participants will test a new medication called NKT5097 to see how safe it is and what side effects it may cause.
Recruiting
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity
PHASE3 Anchorage, Alaska +4 sites NCT03418961
This trial is looking for patients with breast cancer that has spread to other parts of the body. Participants must be receiving trastuzumab-based treatment and will be monitored for potential heart problems.
Recruiting
An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer.
PHASE4 Tucson, Arizona +4 sites NCT07357597
This trial is looking for patients with certain types of breast or lung cancer who are starting treatment with Dato-DXd. Participants will use a special mouthwash to help prevent mouth sores during their treatment.
Recruiting
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
NA Phoenix, Arizona +4 sites NCT07214532
This trial is looking for women and men with early-stage breast cancer that is hormone receptor-positive and HER2-negative. Participants will take a test to help decide if they should start a specific treatment along with hormone therapy, or continue only hormone therapy while being monitored.
Recruiting
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
N/A Birmingham, Alabama +4 sites NCT03452774
This trial is looking for cancer patients to see if an AI tool can help match them to clinical trials. Patients will have their cancer-related biomarkers evaluated to find suitable studies for their condition.
Recruiting
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
PHASE2 Birmingham, Alabama +4 sites NCT05564377
This trial is looking for patients with advanced solid tumors that have either spread to nearby areas or other parts of the body and who have not improved with standard treatments. Participating involves having genetic testing and possibly a biopsy to help find a suitable treatment that targets specific genetic changes in the tumor.
Recruiting

Where the Breast Cancer studies are in West Virginia

  • West Virginia University Healthcare, Morgantown7 trials
  • Camden Clark Medical Center, Parkersburg5 trials
  • Edwards Comprehensive Cancer Center, Huntington5 trials
  • West Virginia University, Morgantown5 trials
  • United Hospital Center, Bridgeport4 trials
  • WVUH-Berkely Medical Center, Martinsburg4 trials

Counts are recruiting studies listing at least one site in West Virginia, from ClinicalTrials.gov, refreshed every two days.

Breast Cancer clinical trials in West Virginia: common questions

How many Breast Cancer clinical trials are recruiting in West Virginia?
TrialFinder currently lists 24 recruiting Breast Cancer clinical trials with study sites in West Virginia. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Breast Cancer clinical trials located in West Virginia?
Study sites for the Breast Cancer trials listed on this page include Morgantown. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Breast Cancer clinical trial in West Virginia?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Breast Cancer trials in West Virginia also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Breast Cancer clinical trial in West Virginia?
Each study sets its own criteria based on age, Breast Cancer diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need to know my receptor status to join a breast cancer trial?
It helps, because trials are organized by subtype, but the study site reads it from your pathology report. If a trial needs a test you have not had, such as HER2-low or a BRCA result, the site arranges it.
Are there trials for early-stage breast cancer?
Yes. Early-stage trials enroll before surgery, after surgery, or during the years of hormone therapy that follow, and test ways to lower the chance the cancer returns. The listing says which window it enrolls in.
Will a trial replace the treatment my oncologist planned?
Sometimes it is the plan, with a new drug added or compared; sometimes it is an alternative to discuss. Bring the trial page to your oncologist, who can refer you to the site or advise on timing.
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

Check Your Eligibility

Create a free profile and our AI will match you to Breast Cancer trials near you in West Virginia.

Get Matched — Free
No insurance required

Breast cancer trials test new chemotherapy regimens, immunotherapy combinations, targeted therapies, and early-detection methods across all stages of breast cancer.

All Breast Cancer trials →