Breast Cancer Trials / Trials in New Hampshire
33 Recruiting Trials

Clinical Trials
for Breast Cancer in New Hampshire

33 clinical trials for Breast Cancer are currently recruiting participants at study sites in New Hampshire. Study-related care is provided at no cost.

33
Recruiting trials
24
Study sites
9
Cities
10
Industry-sponsored
8
Phase 2
11
Phase 3

Breast Cancer clinical trials in New Hampshire: what to expect

Breast cancer trials are sorted first by subtype, because the treatments differ: hormone-receptor-positive, HER2-positive (including the newer HER2-low group) and triple-negative disease each have their own studies. Most recruiting trials test a new drug or combination, including targeted pills, antibody-drug conjugates and immunotherapy, either for metastatic cancer or before and after surgery for early-stage disease. Others study less surgery or radiation, ways to reduce recurrence, and screening for people at higher risk.

In New Hampshire, recruiting breast cancer studies are concentrated in Lebanon, Concord, Manchester and Londonderry, with sites in 5 other cities. 10 of the 33 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who breast cancer trials usually look for

Listings name the subtype, the stage (early or metastatic) and how many treatments you may already have had. Early-stage trials often enroll between diagnosis and surgery, or in the months after surgery; metastatic trials usually enroll when a treatment has stopped working. Some specify menopausal status or a particular mutation (BRCA, PIK3CA, ESR1), which the site can test for. Nearly all require that you are well enough for daily activity and that recent blood work is adequate.

Your receptor status is on your pathology report; the site will confirm it from that report, so you do not need to know it by heart to ask.

What taking part involves

Screening reviews your pathology and scans and adds blood work, sometimes a biopsy. Treatment then runs in cycles, with infusions every two to three weeks or daily pills, and scans every two to three months to check the response. Early-stage trials follow you for years after treatment ends, usually with a visit or call every few months. Study drugs and study-specific tests are free; care you would receive anyway is billed to insurance as usual. Placebo, when used, is added to standard treatment.

Questions worth asking the study team

How the study treatment compares with what your oncologist would otherwise recommend; whether the trial is randomized and what the other arm receives; what happens if the cancer grows or returns; and how visits fit around work and family. Many trials now allow some visits at a local clinic.

Showing 20 of 33 recruiting Breast Cancer trials in New Hampshire

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
PHASE3 Hot Springs, Arkansas +4 sites NCT07085767
This trial is looking for adults with advanced breast cancer that hasn’t been treated before. Participants will receive palazestrant with ribociclib or letrozole with ribociclib to see which treatment works better.
Recruiting
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
PHASE3 Birmingham, Alabama +4 sites NCT05879926
This trial is looking for premenopausal women with early-stage breast cancer that is hormone receptor-positive. Participants will receive hormone therapy and may also get chemotherapy to see if it helps them live longer without cancer returning.
Recruiting
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
PHASE3 Phoenix, Arizona +4 sites NCT06072612
This trial is looking for adults with advanced or locally recurrent breast cancer who have run out of treatment options. Participants will receive treatment with the Bria-IMT regimen and a checkpoint inhibitor to see how well it works compared to other standard treatments.
Recruiting
ATEMPT 2.0: Adjuvant T-DM1 vs TH
PHASE2 San Francisco, California +4 sites NCT04893109
This trial is looking for patients with early-stage breast cancer that tests positive for HER2. Participants will receive one of two treatment options after surgery to see how well they work.
Recruiting
Evaluating the Use of a Medication 'Switch' vs Guideline-directed Interventions for Relieving Side Effects of Aromatase Inhibitors Among Breast Cancer Patients
PHASE2 Lebanon, New Hampshire NCT07071038
This trial is looking for women with early-stage breast cancer who are starting treatment with aromatase inhibitors. Taking part involves managing side effects to help women stay on their treatment for a minimum of two years.
Recruiting
Pilot SMART of a Remotely Delivered, Physical Activity Intervention for Breast Cancer Survivors
NA Lebanon, New Hampshire NCT07706556
This trial is looking for breast cancer survivors who want to increase their physical activity. Participants will meet with an exercise specialist and wear an activity monitor to track their progress.
Recruiting
A Randomized Two-Arm Proof of Concept Study Testing A Novel Approach to Exercise Promotion Based on Affect-regulation
NA Lebanon, New Hampshire NCT06258993
This trial is looking for breast cancer survivors who completed treatment within the last 5 years. Participants will either follow an exercise plan based on their feelings or one based on effort, while wearing an activity monitor and completing surveys over 12 weeks.
Recruiting
MRg-NIRS Imaging System Breast Cancer Trial
NA Lebanon, New Hampshire NCT06400563
This trial is looking for women with breast cancer to see how a new imaging method can help in their treatment. Participants will receive MR-guided near-infrared imaging along with standard care.
Recruiting
A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy
PHASE3 Birmingham, Alabama +4 sites NCT05774951
This trial is looking for people with early breast cancer who have completed at least 2 years of standard treatment. Participants will receive camizestrant to see if it helps improve their outcomes compared to standard therapy.
Recruiting
Genetically-informed Therapy for ER+ Breast Cancer Post-CDK4/6 Inhibitor
PHASE2 Lebanon, New Hampshire NCT05933395
This trial is looking for post-menopausal women with advanced ER+ breast cancer who have been previously treated with certain cancer medications. Participants will undergo tests and possibly receive a new treatment designed for their specific cancer profile.
Recruiting
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
PHASE3 Birmingham, Alabama +4 sites NCT04852887
This trial is looking for women with early-stage hormone-sensitive breast cancer who are interested in taking part in a study on surgery and hormone therapy without radiation. Participants will need to meet specific health criteria to join.
Recruiting
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
PHASE3 Birmingham, Alabama +4 sites NCT06058377
This trial is looking for women with hormone receptor positive, HER2 negative stage II-III breast cancer. Participants will receive standard chemotherapy along with an immunotherapy drug called durvalumab to see if it helps prevent cancer from coming back.
Recruiting
The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study
PHASE3 Chandler, Arizona +4 sites NCT06377852
This trial is looking for older patients with metastatic breast cancer to test different dosing strategies for two medications. Participants will help researchers understand how well these strategies work and which might be better tolerated.
Recruiting
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
PHASE3 Phoenix, Arizona +4 sites NCT06876714
This trial is looking for adults with HER2-positive breast cancer who have no residual invasive disease after chemotherapy. Participants will receive either 6 or 12 months of HER2-targeted medications to see which duration works best.
Recruiting
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
PHASE3 Birmingham, Alabama +4 sites NCT05812807
This trial is looking for people with early-stage triple-negative breast cancer who had no cancer left after previous treatments. Participants will either continue receiving pembrolizumab or just be monitored after surgery to see which approach works better to prevent cancer from coming back.
Recruiting
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
PHASE3 Birmingham, Alabama +4 sites NCT05929768
This trial is looking for women with early-stage triple negative breast cancer. Participants will receive a shorter treatment plan involving chemotherapy and immunotherapy without a certain type of drug called anthracyclines.
Recruiting
Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer
PHASE2 Orange, California +4 sites NCT03606967
This trial is looking for adults with advanced triple negative breast cancer. Participants will receive a combination of chemotherapy and a personalized vaccine to see how well it works for their condition.
Recruiting
STUDY02001740;22SCH740: Estradiol For ER+ Advanced Breast Cancer (ESTHER)
PHASE2 Lebanon, New Hampshire NCT05716516
This trial is looking for post-menopausal women with ER+ breast cancer that has spread or cannot be treated with cure. Participants will be receiving treatment with 17b-estradiol and must have had prior hormone therapy.
Recruiting
A Study of Tetrathiomolybdate (TM) Plus Capecitabine
PHASE1 Lebanon, New Hampshire +2 sites NCT06134375
Recruiting
Safety Study of MELK Inhibitor to Treat Patients With Advanced Breast Cancer and Triple Negative Breast Cancer
PHASE1 Lebanon, New Hampshire +4 sites NCT02926690
This trial is looking for women aged 18 and older with locally advanced or metastatic breast cancer that is not responding to standard treatments. Participants will take OTS167 in capsule form and be monitored for their health during the study.
Recruiting
See all 33 Breast Cancer trials in New Hampshire

Where the Breast Cancer studies are in New Hampshire

Research sites running the most studies
  • New Hampshire Oncology Hematology PA-Concord, Concord7 trials
  • Solinsky Center for Cancer Care, Manchester7 trials
  • Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon6 trials
  • Dartmouth-Hitchcock Medical Center, Lebanon6 trials
  • Dartmouth Hitchcock Medical Center, Lebanon4 trials
  • Dartmouth Cancer Center, Lebanon2 trials
By city

Counts are recruiting studies listing at least one site in New Hampshire, from ClinicalTrials.gov, refreshed every two days.

Breast Cancer clinical trials in New Hampshire: common questions

How many Breast Cancer clinical trials are recruiting in New Hampshire?
TrialFinder currently lists 33 recruiting Breast Cancer clinical trials with study sites in New Hampshire. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Breast Cancer clinical trials located in New Hampshire?
Study sites for the Breast Cancer trials listed on this page include Lebanon. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Breast Cancer clinical trial in New Hampshire?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Breast Cancer trials in New Hampshire also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Breast Cancer clinical trial in New Hampshire?
Each study sets its own criteria based on age, Breast Cancer diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need to know my receptor status to join a breast cancer trial?
It helps, because trials are organized by subtype, but the study site reads it from your pathology report. If a trial needs a test you have not had, such as HER2-low or a BRCA result, the site arranges it.
Are there trials for early-stage breast cancer?
Yes. Early-stage trials enroll before surgery, after surgery, or during the years of hormone therapy that follow, and test ways to lower the chance the cancer returns. The listing says which window it enrolls in.
Will a trial replace the treatment my oncologist planned?
Sometimes it is the plan, with a new drug added or compared; sometimes it is an alternative to discuss. Bring the trial page to your oncologist, who can refer you to the site or advise on timing.
Breast Cancer Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About Breast Cancer Trials

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