Effects of Glucose Control in Type 2 Diabetes
Reversibility of Brain Glucose Transport in Type 2 Diabetes Mellitus (T2DM)
Recruiting
N/A
Interventional Study
Diabetes Mellitus, Type 2
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 60
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 24 (estimated)
- Sponsor
- Yale University · Other
Who this trial is looking for
This trial is looking for adults with type 2 diabetes to understand how better control of blood sugar affects the brain. Participants will be monitored over 12 weeks to see if improving blood sugar levels can help reverse some brain changes.
Are You a Good Fit for This Trial?
You may be able to join if
- I have been diagnosed with type 2 diabetes
- I am aged 18-60
- I have an HbA1c level greater than 7.5%
- My BMI is 18 kg/m2 or more
- I am willing to follow a diabetes management plan
- I can provide consent to participate
You may not be able to join if
- My creatinine level is over 1.5 mg/dL
- My hemoglobin is under 10 mg/dL or hematocrit is too low
- I have untreated thyroid disease
- I have uncontrolled high blood pressure
- I have a neurological disorder
- I have untreated psychiatric issues
- I am pregnant, breastfeeding, or trying to get pregnant
- I cannot safely enter an MRI machine
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The goal of this clinical trial is to learn about the effects of high blood glucose levels in the brain and assess if the changes seen in individuals with poorly control T2DM can be reversed with good glucose control.
The main question\[s\] it aims to answer are:
* To determine, whether abnormalities in brain glucose transport seen in individuals with uncontrolled diabetes, can be improved with …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Provision of signed and dated informed consent form
* Stated willingness to comply with all study procedures and availability for the duration of the study
* Male or female, aged 18-60
* medical history for Type 2 diabetes
* HbA1c \> 7.5%, BMI ≥18 kg/m2
* Be willing to adhere …
Contacts