No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 75
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
500 (estimated)
Sponsor
University of Michigan · Other
Who this trial is looking for
This trial is looking for people with obesity who want to lose weight. Participants will either join the MiWeigh program or receive basic weight loss information. They will have virtual visits and report their weight weekly if they are in the program group.
Are You a Good Fit for This Trial?
Must not be takingAnti-obesity medication
Rules you outType 1 diabetesDementiaChronic kidney diseaseAlcohol dependenceOpioid dependenceAnorexiaBulimia
You may be able to join if
I have a BMI of 30 or higher
I am diagnosed with type 2 diabetes, prediabetes, or hypertension
I speak English
I am interested in losing weight
I can complete assessments as required
I can use the electronic health records patient portal
I can report my weight weekly by text if chosen for the program
I am able to see a provider virtually up to four times a year
You may not be able to join if
I have lost 5% or more of my weight in the past year
I have participated in a Weight Navigation Program before
I am pregnant, planning to get pregnant, or breastfeeding
I am in another weight-loss program
I take anti-obesity medication
I have ever been diagnosed with type 1 diabetes
I have serious uncontrolled mental health conditions
I have chronic kidney disease, stage 4 or higher
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The main purpose of this study is to determine whether people who participate in MiWeigh lose more weight than people who receive information about weight loss strategies and programs. The researchers also want to learn what parts of the program do and do not work and why. If the program is effective, the researchers want to learn how other health care systems could offer this program.
The overar…
The main purpose of this study is to determine whether people who participate in MiWeigh lose more weight than people who receive information about weight loss strategies and programs. The researchers also want to learn what parts of the program do and do not work and why. If the program is effective, the researchers want to learn how other health care systems could offer this program.
The overarching aim of the MiWeigh Study is to better help patients prevent, manage, or reverse obesity-related chronic conditions.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Body Mass index (BMI) 30 kilogram per square meter or higher
* Diagnosed with one or more of the following weight-related conditions:
* Type 2 Diabetes
* Prediabetes Mellitus
* Hyperlipidemia (HLP)
* Hypertension (HTN)
* Polycystic Ovary Syndrome (PCOS)
* Obstruct…
Inclusion Criteria:
* Body Mass index (BMI) 30 kilogram per square meter or higher
* Diagnosed with one or more of the following weight-related conditions:
* Type 2 Diabetes
* Prediabetes Mellitus
* Hyperlipidemia (HLP)
* Hypertension (HTN)
* Polycystic Ovary Syndrome (PCOS)
* Obstructive Sleep Apnea (OSA) and/or
* Metabolic dysfunction-associated steatotic liver disease (MASLD)
* Speaks English
* Interest in losing weight
* Willingness to complete assessments per study protocol
* Willing and able to use the Electronic health records patient portal to respond to messages
* Willing to report weight weekly by text if randomized to intervention arm
* Able to see provider virtually at certain days/times up to four times in a year
Exclusion Criteria:
* ≥ 5% weight loss within the prior 12 months
* Has had a Weight Navigation Program visit in past
* Pregnant, planning a pregnancy, or breastfeeding in the next year
* Ongoing participation in another weight-loss program
* Taking an anti-obesity medication
* Ever diagnosed with Type 1 Diabetes Mellitus (per protocol)
* Dementia
* Serious uncontrolled mental health conditions as indicated (per protocol)
* Chronic kidney disease, Stage 4 or higher
* Alcohol dependence and opioid dependence (per protocol)
* History of anorexia or bulimia
* Bariatric/ gastric bypass surgery, gastric sleeve surgery, or gastric balloon procedure in last year
* Currently enrolled in an interventional research study that is examining how a diet, program, or drug might: promote physical exercise, healthy eating habits, or weight loss; lower blood pressure; or lower blood sugar
* Not planning to live in local area over the next year
* Intensive cancer treatment such as bone marrow transplant, chemotherapy, radiation, or cancer related surgery (not including hormonal chemotherapy like Tamoxifen) in last six months or next 12 months
* Other serious health issues or personal concerns that could prevent participant from completing study
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