Pathological Changes in Multiple Sclerosis
Pathological Basis of MRI Signal Changes in Multiple Sclerosis
Recruiting
Observational Study
Multiple Sclerosis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 120
- Sex
- Any
- Study type
- Observational
- Participants needed
- 250 (estimated)
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS) · NIH
Who this trial is looking for
This trial is looking for adults with multiple sclerosis or a similar brain condition. Participants will undergo various tests including MRIs and eye exams, and will be followed for their health over time.
Are You a Good Fit for This Trial?
You may be able to join if
- I am 18 years old or older.
- I have been diagnosed with multiple sclerosis or a similar brain condition.
- I am willing to return for follow-up visits at least once a year.
- I can give informed consent to participate.
- I am able to participate in study procedures.
- I agree to have an autopsy after my death.
- I am a NIH employee or staff member.
You may not be able to join if
- I am unwilling to allow my samples and data to be shared for future studies.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Background:
Multiple sclerosis (MS) is a disease that damages the central nervous system (brain and spinal cord). This leads to increased physical disability over time. The disease is lifelong once it begins. Researchers want to learn more about MS s stages and follow them until a person s death.
Objective:
To understand how the physical and clinical signs of MS relate to its changes over time.…
Trial Locations
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Eligibility Criteria
* INCLUSION CRITERIA:
* Diagnosis of MS according to consensus criteria at the time of enrollment OR diagnosis of a disease that shares clinical, imaging, or biological features with MS OR individuals without known CNS disease.
* Age greater than or equal to 18.
* Able to participate in study proced…
Contacts