Prospective Investigation of Multiple Sclerosis in the Three Rivers Region
Recruiting
Observational Study
Multiple Sclerosis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
7 and older
Sex
Any
Study type
Observational
Participants needed
7,500 (estimated)
Sponsor
University of Pittsburgh · Other
Who this trial is looking for
This trial is looking for people diagnosed with multiple sclerosis, as well as healthy individuals, to help researchers understand how the disease affects people differently. Participants will be observed over a long period of time, up to 30 years.
Are You a Good Fit for This Trial?
You may be able to join if
I am 7 years or older
I can give consent or have permission from my parent if I am a child
I have been diagnosed with multiple sclerosis or related disorders
I have had an abnormal MRI scan related to multiple sclerosis
I have no known personal history of multiple sclerosis if I am a healthy control
I do not have other chronic diseases
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
In this longitudinal prospective natural history study of multiple sclerosis (MS), the overarching goal is to understand the factors that influence individual variation in disease trajectory and treatment response and pave the way for realizing precision medicine in MS. Because MS is a chronic neurological disorder, this observational cohort study will span a 30-year time frame.
Trial Locations
Loading…
Loading trial locations…
Facility
City
State
Country
Status
Eligibility Criteria
Inclusion Criteria:
* Inclusion criteria for MS patients include:
1. Age 7 years or older
2. Willing and able to provide consent (for \>=18 years) or assent with permission from at least one of the child's parents (for \<18 years)
3. Diagnosis of multiple sclerosis or related disorders, incl…
Inclusion Criteria:
* Inclusion criteria for MS patients include:
1. Age 7 years or older
2. Willing and able to provide consent (for \>=18 years) or assent with permission from at least one of the child's parents (for \<18 years)
3. Diagnosis of multiple sclerosis or related disorders, including a first central nervous system demyelinating episode with a positive MRI scan or abnormal MRI scans characteristic of MS but no clinical symptoms of the disease
* For healthy controls:
1. Age 7 years or older
2. Willing and able to provide consent (for \>=18 years) or assent with permission from at least one of the child's parents (for \<18 years)
3. No known personal history of multiple sclerosis or related disorders
4. No other chronic diseases
5. Family members, unrelated household controls, or controls from the general population could be eligible
There is no exclusion criteria.
Picking one helps us show the most relevant trials first.
Your results are loading in the background — you can
change this any time from the results page.
Set your location to continue
Find My Trials uses your location to surface clinical trials near you.
Add your city or zip code to your profile and try again.
