Retinal Imaging for Neurodegenerative Diseases
Retinal Imaging in Neurodegenerative Disease
Recruiting
Observational Study
Alzheimer's Disease
Mild Cognitive Impairment
Parkinson's Disease
Multiple Sclerosis
Huntington Disease
Lewy Body Dementia
Frontotemporal Dementia
Amyotrophic Lateral Sclerosis (ALS)
APOE-4 Positive
Traumatic Brain Injury
Concussion
Post-Traumatic Stress Disorder
Down Syndrome
Neuro-Degenerative Disease
Normal Cognition
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 2,000 (estimated)
- Sponsor
- Duke University · Other
Who this trial is looking for
This trial is looking for adults with neurodegenerative diseases or no neurodegenerative disease. Participants will undergo imaging tests to assess their eye health.
Are You a Good Fit for This Trial?
You may be able to join if
- I have a neurodegenerative disease
- I do not have a neurodegenerative disease
You may not be able to join if
- I cannot cooperate with tests or have other eye conditions affecting imaging
- I have had eye surgery other than cataract surgery
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield (UWF) fundus photography to assess the structure and function of the retinal and choroidal microvasculature and structure in persons with mild cognitive impairment (MCI) and Alzheimer's Disease (AD), Parkinson's Disease (PD), or other neurod…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adults with neurodegenerative disease ((MCI, PD, AD, FTD, DLB, ALS, MS, HD, TBI, concussion, PTSD and other neurodegenerations as well as Down Syndrome)
* Adults without neurodegenerative disease
Exclusion Criteria:
* Inability to cooperate with or complete testing or other …
Contacts