Amylin and Its Role in Diabetic Nerve Damage
A Causative Role for Amylin in Diabetic Peripheral Neuropathy
Recruiting
Observational Study
Type2 Diabetes
Peripheral Neuropathy
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 40 (estimated)
- Sponsor
- Zabeen Mahuwala, MD · Other
Who this trial is looking for
This trial is looking for people with Type-2 diabetes and nerve pain. Participants will provide blood and skin samples and undergo tests to measure their sensitivity to heat, cold, and pressure.
Are You a Good Fit for This Trial?
You may be able to join if
- I have been diagnosed with Type-2 diabetes.
- I have mild-to-severe peripheral neuropathy.
You may not be able to join if
- I have not been diagnosed with Type-2 diabetes.
- I perform average or above average on Nerve Conduction Velocity tests.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Three pieces of information lead to the basis for this study:
1. Individuals with Type-2 diabetes commonly develop peripheral neuropathy.
2. Increased production of the hormone amylin occurs in individuals who have Type-2 diabetes.
3. Aggregations of amylin was found in the peripheral vasculature of rats that overexpressed human amylin.
The purpose of this study is to determine whether a correla…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Subject has been diagnosed with Type-2 Diabetes.
* Subject shows mild-to-severe peripheral neuropathy, as determined by Nerve Conduction Velocity (NCV) tests.
Exclusion Criteria:
* Subject has not been diagnosed with Type-2 Diabetes.
* Subject shows average, or above average…
Contacts