Tau Imaging Study for Alzheimer Disease
UAB Alzheimer's Disease Center Core Cohort - Tau Imaging Substudy
Recruiting
Phase 1
Interventional Study
Alzheimer Disease
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 50 and older
- Sex
- Any
- Trial phase
- Phase 1
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 160 (estimated)
- Sponsor
- University of Alabama at Birmingham · Other
Who this trial is looking for
This trial is looking for participants to help researchers measure tau levels in the brain of individuals with Alzheimer’s disease. Participants will also be involved in another study that checks for amyloid levels and cognitive status.
Are You a Good Fit for This Trial?
You may be able to join if
- I am enrolled in the UAB-ADC study.
- I am enrolled in the UAB-ADC amyloid-PET study.
- I am a woman of childbearing potential and have a negative pregnancy test.
- I am post-menopausal or have had surgical sterilization.
You may not be able to join if
- I do not meet the exclusion criteria for the UAB-ADC study.
- I cannot undergo MRI or PET imaging.
- I cannot participate in the imaging studies due to the severity of my dementia.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The primary objective of this study is to measure the concentration and the regional brain distribution of pathologic tau deposition using the PET tracer AV-1451 in participants in the UAB-ADC cohort. The amount and distribution of AV-1451 in the brain will be correlated to demographic, clinical, genetic, and biospecimen data acquired through the separate ongoing UAB-ADC study. Assessment of inter…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Enrollment in the UAB-ADC study under a separate IRB-approved research protocol.
2. Enrollment in the UAB-ADC amyloid-PET substudy under a separate IRB-approved research protocol. The amyloid-PET study does not have to have been completed prior to enrollment and participation…
Contacts