No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
60 and older
Sex
Female
Trial phase
Phase 4
Study type
Interventional
Purpose
Diagnostic
Participants needed
614 (estimated)
Sponsor
Mayo Clinic · Other
Who this trial is looking for
This trial is looking for women aged 60 and older to learn about the effects of ovarian hormones on aging and Alzheimer's disease. Participants will need to provide consent and be healthy enough to join the study.
Are You a Good Fit for This Trial?
You may be able to join if
I am a woman
I am 60 years old or older
I participated in this study before
I am more than six months post chemotherapy or major surgery
I am willing and able to sign informed consent
You may not be able to join if
I cannot read and speak English
I am in hospice
I am claustrophobic
I have QT prolongation and will undergo Tau imaging
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The researchers are trying to determine whether ovarian hormones are associated with aging processes and with the risk of developing Alzheimer's disease in women.
Trial Locations
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Facility
City
State
Country
Status
Eligibility Criteria
Mayo Clinic Rochester-
Inclusion Criteria:
* Women who previously participated in this study
* Currently aged 60 years and older
* More than six months post chemotherapy or major surgery requiring general anesthesia
* Willing and able to sign informed consent
Exclusion Criteria:
* Not able to re…
Mayo Clinic Rochester-
Inclusion Criteria:
* Women who previously participated in this study
* Currently aged 60 years and older
* More than six months post chemotherapy or major surgery requiring general anesthesia
* Willing and able to sign informed consent
Exclusion Criteria:
* Not able to read and speak English
* In hospice
* Claustrophobic
* If undergoing Tau imaging, cannot have QT Prolongation
Mayo Clinic Jacksonville-
Inclusion Criteria:
* African American Women
* Currently aged 60 years and older
* More than six months post chemotherapy or major surgery requiring general anesthesia
* Willing and able to sign informed consent
Exclusion Criteria:
* Not able to read and speak English
* In hospice
* Claustrophobic
* If undergoing Tau imaging, cannot have QT Prolongation
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