Bariatric Surgery for Obesity Management

Long-term, Substantial Weight Loss and Insulin Regulation of Lipolysis

Recruiting N/A Interventional Study
Obesity, Morbid
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 65
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
30 (estimated)
Sponsor
Mayo Clinic · Other
Who this trial is looking for

This trial is looking for people with obesity who want to understand how weight loss affects insulin and fat breakdown. Participants will be studied before and after having bariatric surgery.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have a BMI between 40 and 50
  • I do not have any active illness that interferes with mobility

You may not be able to join if

  • I have been diagnosed with Type 1 or Type 2 diabetes
  • I have active coronary artery disease
  • I participate in structured exercise more than 2 times a week
  • I smoke
  • I take medications that affect fat metabolism
  • I have kidney problems
  • I have chronic liver disease
  • I am pregnant or breastfeeding

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

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About This Trial

It is not known how much improvement in insulin regulated lipolysis (the breakdown of triglycerides) occurs following substantial, sustained weight loss. Researchers will test the effects of inflammation and lipolysis regulation in people before and after bariatric surgery (sleeve gastrectomy) to answer these questions.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * BMI 40 - 50 kg/m2. * Mo active physical illness that would interfere with mobility or weight loss after bariatric surgery Exclusion Criteria: * Type 1 or Type 2 Diabetes diagnosis or fasting plasma glucose ≥126 mg/dL * Active coronary artery disease * Participation in struct…
Contacts

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