No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
40 – 89
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
54 (estimated)
Sponsor
VA Office of Research and Development · Federal
Who this trial is looking for
This trial is looking for Veterans who have had a lower leg amputation without trauma and face challenges when walking. Participants will take part in training aimed at improving their walking ability and reducing any pain or other issues that arise from their condition.
Are You a Good Fit for This Trial?
You may be able to join if
I have a non-traumatic transtibial amputation.
I have diabetes mellitus or peripheral artery disease.
I can walk in the community without any support devices.
I have a step length asymmetry while walking.
It has been at least 6 months since my amputation.
You may not be able to join if
I have an unstable heart condition.
I have an active cancer treatment.
I have an acute systemic infection.
My amputation was due to trauma or cancer.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The population of older Veterans with non-traumatic lower limb amputation is growing. Following lower limb amputation, asymmetrical movements persist during walking and likely contribute to disabling sequelae including secondary pain conditions, poor gait efficiency, impaired physical function, and compromised skin integrity of the residual limb. This study seeks to address chronic gait asymmetry …
The population of older Veterans with non-traumatic lower limb amputation is growing. Following lower limb amputation, asymmetrical movements persist during walking and likely contribute to disabling sequelae including secondary pain conditions, poor gait efficiency, impaired physical function, and compromised skin integrity of the residual limb. This study seeks to address chronic gait asymmetry by evaluating the efficacy of two error-manipulation gait training programs to improve gait symmetry for Veterans with non-traumatic lower limb amputation. Additional this study will evaluate the potential of error-manipulation training programs to improve secondary measures of disability and residual limb skin health. Ultimately, this study aims to improve conventional prosthetic rehabilitation for Veterans with non-traumatic amputation through gait training programs based in motor learning principles, resulting in improved gait symmetry and lower incidence of long-term disability after non-traumatic lower limb amputation.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Unilateral, non-traumatic, transtibial amputation
* Diabetes mellitus and/or peripheral artery disease
* Able to ambulate in the community without assistive device
* Step length asymmetry during walking (\>1.0 asymmetry index.)
* 6 months since amputation
Exclusion Criteria:
…
Inclusion Criteria:
* Unilateral, non-traumatic, transtibial amputation
* Diabetes mellitus and/or peripheral artery disease
* Able to ambulate in the community without assistive device
* Step length asymmetry during walking (\>1.0 asymmetry index.)
* 6 months since amputation
Exclusion Criteria:
* Unstable heart condition
* Including unstable angina, uncontrolled cardiac dysrhythmia, acute myocarditis, hypertension, and acute pericarditis
* Acute systemic infection
* Active cancer treatment
* Traumatic or cancer related amputation etiology
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