Monitoring Immune Response in Cardiac Surgery Patients
Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery
Recruiting
Observational Study
Congenital Heart Disease
Coagulation
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Sex
- Any
- Study type
- Observational
- Participants needed
- 100 (estimated)
- Sponsor
- Boston Children's Hospital · Other
Who this trial is looking for
This trial is looking for patients of all ages who are scheduled for complex heart surgery using a heart-lung machine. Participants will have their blood tested before, during, and after the surgery to study immune responses.
Are You a Good Fit for This Trial?
You may be able to join if
- I am undergoing complex cardiac surgery with a heart-lung machine.
You may not be able to join if
- I need an emergency surgery and cannot review consent for more than 1 hour.
- I am in a very poor health condition and rated ASA 5.
- I have a blood or cancer disease.
- I am a Jehovah's Witness.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The goal of this proposal is to prospectively collect data from a series of 200 patients (all ages) undergoing complex cardiac surgical procedures involving cardiopulmonary bypass (CPB) to:
1. Measure the number of blood activated circulating monocytes before, during and after cardiac surgery and serum GABA and pro-inflammatory cytokine levels
2. Understand the correlation between GABA and inflam…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients (all ages) undergoing complex cardiac surgical procedures with CPB.
Exclusion Criteria:
* undergoing an emergent procedure and do not have more than 1 hour ahead of time to review the consent
* patient in a moribund condition American Society of Anesthesiology (ASA …
Contacts