An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy
Recruiting
N/A
Interventional Study
Kidney Cancer
Renal Cell Carcinoma
Clear Cell Carcinoma
Urothelial Carcinoma
Metastatic Kidney Cancer
Metastatic Urothelial Carcinoma
Papillary Renal Cell Carcinoma
Chromophobe Renal Cell Carcinoma
Fumarate Hydratase Deficiency
Succinate Dehydrogenase-Deficient Renal Cell Carcinoma
HLRCC
Hereditary Leiomyomatosis and Renal Cell Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 600 (estimated)
- Sponsor
- University of Texas Southwestern Medical Center · Other
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About This Trial
The purpose of this study is to understand the metabolism of cancers involving the kidney, including renal cell carcinomas and urothelial cell carcinomas, and how kidney cancers use different types of fuel to support tumor growth. This study uses specially labeled nutrient tracers of compounds normally found circulating in the blood. The nutrients (glucose, fructose, glutamine, acetate, and lactat…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients must have radiographic evidence of known or probable kidney or urothelial cancer requiring surgical biopsy or excision.
* Age ≥ 18 years
* Subjects of all races and ethnic origins
* The willingness to sign and ability to understand a written informed consent.
* Patien…
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