Exercise and Sleep Study for Alzheimer's and Dementia

Combating Alzheimer's Through Sleep and Exercise

Recruiting N/A Interventional Study
Dementia Mild Cognitive Impairment (MCI) Cognitively Unimpaired Alzheimer's Dementia (AD)
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
55 – 80
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
60 (estimated)
Sponsor
University of Miami · Other
Who this trial is looking for

This trial is looking for people aged 55-80 to explore how sleep and exercise can improve thinking and heart health. Participants will engage in moderate exercise and track their sleep using specific devices.

Are You a Good Fit for This Trial?
Must not be taking Anti-amyloid monoclonal antibodies
Rules you out Alzheimer'sDementia

You may be able to join if

  • I am aged between 55 and 80 years.
  • I can walk safely on my own.
  • I can complete moderate exercise safely.
  • I can use a Fitbit and/or Elemind devices.
  • I can use a mobile phone or computer.
  • I am willing to provide blood samples.
  • I can speak and understand English.
  • I can report my own cognitive changes.

You may not be able to join if

  • I have severe mobility issues that prevent moderate exercise.
  • I have a medical condition that is unstable or uncontrolled.
  • I cannot complete the screening procedures.
  • I have a severe uncorrected hearing or vision impairment.
  • I have been diagnosed with Alzheimer's or dementia.
  • I cannot engage with digital devices.
  • I regularly exercise more than 150 minutes a week.
  • I have sufficient sleep as defined by sleep efficiency.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial
The Combating Alzheimer's through Sleep and Exercise (CASE) study is an exploratory, hypothesis-generating trial designed to: (1) assess whether improvements in sleep are associated with improvements in cognitive performance and cardiovascular and metabolic health; (2) evaluate the effects of structured, moderate-level aerobic and anaerobic exercise on cognitive performance and cardiovascular and …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Aged 55-80 years at the time of the screening visit 2. Able to ambulate safely and independently 3. Able to safely perform moderate-intensity exercise as per the Physical Activity Readiness Questionnaire (PAR-Q, a validated exercise readiness questionnaire) 4. Able to wear an…
Contacts

Azizi A Seixas, PhD

3052431301

Azizi.seixas@med.miami.edu

CONTACT

Debbie Chung, PhD

3052431301

dxc1729@miami.edu

CONTACT