Xeomin® for Gait Mobility After Stroke

Xeomin® and Gait Related Mobility After Stroke

Recruiting Phase 4 Interventional Study
Stroke
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 79
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
20 (estimated)
Sponsor
Wake Forest University Health Sciences · Other
Who this trial is looking for

This trial is looking for adults who have difficulty walking after a stroke. Participants will receive an injection of Xeomin® in their arms and will be tested on their walking ability before and about a month later.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have been diagnosed with hemiparesis and spasticity from a stroke
  • I can walk at least 10 meters without help from others or devices
  • I have not had any lower limb surgery
  • I have toe-ground clearance while walking without devices
  • I have not received botulinum toxin treatment in the last 4 months

You may not be able to join if

  • I have less than 30 degrees of movement at my ankle, knee, or elbow
  • I have hearing problems that have not been fixed
  • I have injuries that prevent me from safely walking
  • I have difficulty with speech or expressing myself
  • I cannot sense my body's position in space based on a neurologic exam
  • I have fixed contractures in my arms or legs that cannot be corrected
  • I have other neurological disorders or active serious illnesses

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

The aim of the present pilot study is to evaluate the association between change in gait related mobility in ambulatory male and female adult hemiparetic patients before and 4-6-weeks after Xeomin® injection into the upper limb, using two standardized tests of physical function in outpatient rehabilitation that are widely used; the 10-meter walk test and the timed 'up and go' test (TUG).

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Diagnosis of hemiparesis and spasticity secondary to stroke with upper and lower limb spasticity and unilateral motor and/or sensory deficit * No prior surgery to the lower limb * Able to walk at least 10 meters without physical assistance from another person and without an as…
Contacts

Mark A Hirsch, PhD

704-355-7673

Mark.Hirsch@atriumhealth.org

CONTACT

Kiandra Austrie, RN, BSN

704-355-1525

Kiandra.austrie@Advocatehealth.org

CONTACT