Problem Adaptation Therapy for Cognitive Issues and Pain

A Primary Care-Based Psychosocial Intervention To Improve Cognitive & Depression Outcomes in Older Adults With MCI & Early Stage AD

Recruiting N/A Interventional Study
Depression Pain Cognitive Impairment
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
60 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
100 (estimated)
Sponsor
Weill Medical College of Cornell University · Other
Who this trial is looking for

This trial is looking for older adults who have cognitive impairment, depression, and chronic pain. Participants will receive a therapy called Problem Adaptation Therapy for Pain and will be compared to those receiving usual care.

Are You a Good Fit for This Trial?
Must not be taking AntidepressantsCholinesterase inhibitorsMemantine

You may be able to join if

  • I am 60 years old or older
  • I have mild cognitive impairment or early stage Alzheimer's disease
  • I have mild depressive symptoms
  • I have chronic pain that I feel most days
  • I have the ability to consent to participate
  • I have a study partner who can support me

You may not be able to join if

  • I am considered at significant risk for suicide
  • I am too medically or neurologically unstable to join a study
  • I am too psychiatrically unstable to join a therapy study
  • I require psychiatric hospitalization right now
  • I do not speak English fluently

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial

The purpose of the study is to examine the effect of Problem Adaptation Therapy for Pain (PATH-Pain) on cognitive functioning, depression and pain-related disability in 100 older adults with cognitive impairment, chronic pain, and depression. The study will test if PATH-Pain has better cognitive, affective, and functional outcomes than Attention Control Usual Care.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age ≥ 60 years old * MCI or early stage probable or possible AD diagnosis (as defined by Albert et al or McKhann et al) al). Patients will have at least mild cognitive deficits defined by 16 ≤ MoCA ≤ 25. * Montgomery Asberg Depression Rating Scale (MADRS)\[55\] total ≥ 5, whic…
Contacts

Dimtiris Kiosses, PhD

914-997-4381

dkiosses@med.cornell.edu

CONTACT

Laurie Evans, MS

914-682-9100

lad9011@med.cornell.edu

CONTACT