Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT)
Recruiting
N/A
Interventional Study
Depression
HIV-1-infection
Inflammation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 150 (estimated)
- Sponsor
- Florida International University · Other
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About This Trial
The purpose of this randomized controlled trial is to understand how a cognitive-behavioral treatment (a form of psychological treatment) for depression changes the gut microbiome (micro-organisms that regulate the health of the gut), immune system, and the brain functioning in people living with HIV.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age 18 or older
2. Speaks and reads English
3. Verified HIV+ status with antiretroviral medications bearing his/her name
4. Current diagnosis on Major Depressive Disorder (MDD) using a structured clinical interview (DIAMOND) or Hamilton Rating Scale for Depression scores of 7…
Contacts