Lung Surgery for Severe Emphysema or COPD
Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction
Recruiting
N/A
Interventional Study
Emphysema or COPD
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 40 – 75
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 20 (estimated)
- Sponsor
- Beth Israel Deaconess Medical Center · Other
Who this trial is looking for
This trial is looking for patients with severe emphysema or COPD who did not improve after a certain lung treatment. If you join, you may undergo a surgical procedure to help improve your lung function.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 40 to 75 years old.
- I have stable health and take less than 10mg of prednisone daily.
- I have not smoked for the past 4 months and will not smoke during the study.
- I have received the pneumococcus and influenza vaccinations.
- I had less than 350ml of lung volume reduction after my bronchoscopic treatment.
- I still have trouble breathing after that treatment.
- My endobronchial valves are still in place.
- I can complete all required follow-up assessments.
You may not be able to join if
- I produce more than 4 tablespoons of mucus daily.
- I had a heart attack in the past 6 months.
- I have heart failure that is not controlled.
- I have had three or more episodes of pneumonia in the past year.
- I have had three or more episodes of COPD worsening in the last year.
- I have had prior lung surgery.
- I cannot stop anticoagulants or platelet inhibitors for 7 days safely.
- I have uncontrolled pulmonary hypertension or related heart issues.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
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About This Trial
The purpose of this protocol is to perform a pilot prospective controlled clinical trial to evaluate the potential role of lung fissure completion with pleural adhesiolysis strategy (experimental intervention) in severe emphysema/COPD patients with failed bronchoscopic lung volume reduction (BLVR) via the use of endobronchial valves (EBVs) therapy. In select patients, the lung fissure completion w…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age 40 to 75 years.
* Stable with less than 10mg prednisone (or equivalent) daily.
* Nonsmoking for 4 months prior to screening and willing to not smoke during the study duration.
* Current pneumococcus vaccination.
* Current influenza vaccination.
* Target lung volume reducti…
Contacts
No contact information available.