Light, Sound, and Touch Therapy for Parkinson's Disease

High Frequency Light, Sound, and Tactile Stimulation to Improve Motor and Cognitive Deficits in Parkinson's Disease

Recruiting N/A Interventional Study
Parkinson Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
45 – 90
Sex
Any
Study type
Interventional
Purpose
Supportive Care
Participants needed
40 (estimated)
Sponsor
Massachusetts Institute of Technology · Other
Who this trial is looking for

This trial is looking for people with mild Parkinson's disease. Participants will receive therapy using light, sound, and touch while their brain activity is monitored.

Are You a Good Fit for This Trial?
Must be taking Antiparkinsonian agents
Rules you out Atypical Parkinson's syndromeDementiaProgressive Supranuclear PalsyMultiple System AtrophyCorticobasal DegenerationLewy Body dementia

You may be able to join if

  • I have been diagnosed with Parkinson's disease.
  • I am between 45 and 90 years old.
  • I can speak, read, and understand English.
  • I can give informed written consent.
  • I require a stable dose of Parkinson's medication.
  • I have undergone a brain CT or MRI.
  • I have a Montreal Cognitive Assessment score of 26 or higher.
  • I am at Hoehn & Yahr stage 2 to 3.

You may not be able to join if

  • I have a history of psychiatric illness that could be a safety risk.
  • I have been diagnosed with dementia or other neurological conditions.
  • I am currently taking sedative medications.
  • I have changed my medication in the past month.
  • I have had recent drug or alcohol abuse.
  • I have a history of epilepsy, stroke, or seizure in the past 24 months.
  • I am pregnant.
  • I have certain implantable medical devices.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial
Parkinson's disease (PD) impacts different types of neural oscillations in the brain, including beta (13-30Hz) and gamma oscillations (30-80Hz), which contributes to PD's cardinal symptoms of resting tremor, rigidity, bradykinesia (slowness of movement), and gait instability. The investigators' lab has developed a non-invasive method of increasing gamma power in the brain using Gamma Entrainment U…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Subject has Idiopathic PD defined by the cardinal sign, bradykinesia, plus the presence of at least 1 of the following: resting tremor or rigidity and without any other known or suspected cause of Parkinsonism (according to Movement disorder society (MDS) clinical diagnostic c…
Contacts

gamma wave

617-258-7723

gamma.wave@mit.edu

CONTACT

Ana Trisini Lipsanopoulos, BS

617-258-7723

anat13@mit.edu

CONTACT