Regulation of Brain Glucose Metabolism in Type 1 Diabetes
Recruiting
Early Phase 1
Interventional Study
Diabetes Mellitus, Type 1
Hypoglycemia Unawareness
At a Glance
- Age
- 18 – 55
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 16 (estimated)
- Sponsor
- Yale University · Other
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About This Trial
This is a prospective randomized placebo-controlled double-blind crossover pilot study determining the effect of dichloroacetate on brain function under clamped hypoglycemia in T1DM.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
T1DM subjects with:
* a history of severe hypoglycemia and/or hypoglycemia unawareness or
* a history of severe hypoglycemia with a blood glucose \<54 mg/dL, requiring the assistance of another person (with recovery after the administration of oral carbohydrate, intravenous glu…
Contacts