rTMS for Depression in Military Service Members

rTMS for Military TBI-related Depression

Recruiting N/A Interventional Study
Depressive Symptoms Mild Traumatic Brain Injury Concussion
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 55
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
198 (estimated)
Sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine · Other
Who this trial is looking for

This trial is looking for U.S. military service members and veterans who have experienced concussions and are dealing with depression. Participants will receive specific brain stimulation treatments to see if it helps with their symptoms.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am between 18 and 55 years old.
  • I am a current or former U.S. military service member.
  • I have a history of concussion or mild traumatic brain injury.
  • I have at least mild-moderate depressive symptoms.
  • I can provide written consent in English.
  • I have been on a steady medication plan for six weeks.
  • I have been in therapy for twelve weeks.
  • I agree to use effective birth control if I can become pregnant.

You may not be able to join if

  • I have a history of seizures.
  • I have had severe heart disease recently.
  • I currently have a pacemaker or similar device.
  • I have a history of Bipolar Disorder or Schizophrenia.
  • I have tried other brain stimulation treatments within the last 12 weeks.
  • I have attempted suicide in the past six months.
  • I cannot complete the full timeline of the study.
  • I am currently imprisoned or have restricted freedom.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

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About This Trial

The purpose of this study is to investigate the efficacy, safety, and tolerability of two dorsolateral prefrontal cortex (DLPFC) repetitive transcranial magnetic stimulation (rTMS) protocols to alleviate symptoms of depression in United States (U.S.) military service members and veterans with a history of concussion/mild traumatic brain injury (TBI).

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age 18-55 at the time of consent. Older individuals will not be enrolled in this initial trial for reasons of safety and expected reduced efficacy. * Current or former US military service member eligible for care at a Military Treatment Facility (MTF) or Veterans Administratio…
Contacts

Elizabeth N Diaz Nelson, MPH

832-671-9532

elizabeth.nelson.ctr@usuhs.edu

CONTACT