18F-Fluciclovine Imaging for Brain Metastases
Characterization of 18F-Fluciclovine PET Amino Acid Radiotracer in Resected Brain Metastasis
Recruiting
Phase 2
Interventional Study
Brain Metastases
Brain Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 20 (estimated)
- Sponsor
- Baptist Health South Florida · Other
Who this trial is looking for
This trial is looking for patients who have had surgery to remove brain metastases and are planning to receive further treatment. Participants will optionally have a special imaging scan to help doctors assess their condition better.
Are You a Good Fit for This Trial?
You may be able to join if
- I am at least 18 years old
- I have been diagnosed with brain metastasis
- I am planning to have surgery for at least one brain metastasis
- I am planning to have stereotactic radiosurgery after surgery
- I have an Eastern Cooperative Oncology Group (ECOG) performance status of 0-3
You may not be able to join if
- I have had an anaphylactic reaction to 18F-Fluciclovine
- I have evidence of leptomeningeal disease
- I have had prior whole-brain radiation therapy
- I have a contraindication to MRI
- I am pregnant when 18F-Fluciclovine is given
- I expect to be breastfeeding at the time of 18F-Fluciclovine administration and cannot stop for 24 hours
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
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About This Trial
This study is for patients who have had surgery to remove brain metastasis and are planned to have stereotactic radiosurgery (SRS) after their brain surgery. It will be optional for patients to have a pre-surgery 18F-Fluciclovine PET/CT scan. The goal of the study is to determine whether a specific imaging agent, known as 18F-Fluciclovine, will help physicians evaluate the extent of surgery and de…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age ≥ 18 years
2. Performance status, Eastern Cooperative Oncology Group (ECOG) 0-3
3. Radiographic diagnosis of brain metastasis
4. Patient planned for surgical intervention for at least 1 metastasis
5. Patient planned for postoperative SRS
Male or female patients of reprod…
Contacts