No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
30 (estimated)
Sponsor
University of Pittsburgh · Other
Who this trial is looking for
This trial is looking for people with long-term aphasia caused by a stroke. Participants will work on improving their ability to name things and using these skills in daily life.
Are You a Good Fit for This Trial?
You may be able to join if
I have been diagnosed with chronic aphasia after a stroke.
I have trouble on 2 out of 8 sections of the Comprehensive Aphasia Test.
You may not be able to join if
I have a history of other neurological diseases.
I have significant issues understanding language.
I struggle with unmanaged drug or alcohol issues.
I have severe mood or behavioral disorders needing specialized care.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Aphasia is a language disorder caused by stroke and other acquired brain injuries that affects over two million people in the United States and which interferes with life participation and quality of life. Anomia (i.e., word- finding difficulty) is a primary frustration for people with aphasia. Picture-based naming treatments for anomia are widely used in aphasia rehabilitation, but current treatm…
Aphasia is a language disorder caused by stroke and other acquired brain injuries that affects over two million people in the United States and which interferes with life participation and quality of life. Anomia (i.e., word- finding difficulty) is a primary frustration for people with aphasia. Picture-based naming treatments for anomia are widely used in aphasia rehabilitation, but current treatment approaches do not address the long-term retention of naming abilities and do not focus on using these naming abilities in daily life. The current research aims to evaluate novel anomia treatment approaches to improve long-term retention and generalization to everyday life.
This study is one of two that are part of a larger grant. This record is for sub-study 1, which will adaptively balance effort and accuracy using speeded naming deadlines.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Existing diagnosis of chronic (\>6 months) aphasia subsequent to left hemisphere ischemic or hemorrhagic stroke.
* Impaired performance on 2/8 sections of the Comprehensive Aphasia Test.
Exclusion Criteria:
* History of other acquired or progressive neurological disease.
* S…
Inclusion Criteria:
* Existing diagnosis of chronic (\>6 months) aphasia subsequent to left hemisphere ischemic or hemorrhagic stroke.
* Impaired performance on 2/8 sections of the Comprehensive Aphasia Test.
Exclusion Criteria:
* History of other acquired or progressive neurological disease.
* Significant language comprehension impairments
* Unmanaged drug / alcohol dependence.
* Severe diagnosed mood or behavioral disorders that require specialize mental health interventions.
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