No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
32 (estimated)
Sponsor
University of Pittsburgh · Other
Who this trial is looking for
This trial is looking for people with chronic aphasia due to a left hemisphere stroke. Participants will receive a new type of language treatment designed to help improve their ability to name things over time and use those skills in daily life.
Are You a Good Fit for This Trial?
You may be able to join if
I have been diagnosed with chronic aphasia after a left hemisphere stroke.
I have trouble on 2 out of 8 sections of the Comprehensive Aphasia Test.
I have access to high-speed internet.
I can participate in telehealth.
You may not be able to join if
I have a history of another neurological disease.
I have significant language comprehension problems.
I have unmanaged drug or alcohol dependence.
I have severe mood or behavioral disorders that need specialized help.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Aphasia is a language disorder caused by stroke and other acquired brain injuries that affects over two million people in the United States and which interferes with life participation and quality of life. Anomia (i.e., word- finding difficulty) is a primary frustration for people with aphasia. Picture-based naming treatments for anomia are widely used in aphasia rehabilitation, but current treatm…
Aphasia is a language disorder caused by stroke and other acquired brain injuries that affects over two million people in the United States and which interferes with life participation and quality of life. Anomia (i.e., word- finding difficulty) is a primary frustration for people with aphasia. Picture-based naming treatments for anomia are widely used in aphasia rehabilitation, but current treatment approaches do not address the long-term retention of naming abilities and do not focus on using these naming abilities in daily life. The current research aims to evaluate novel anomia treatment approaches to improve long-term retention and generalization to everyday life.
This study is one of two that are part of a larger grant. This record is for sub-study 2, which will evaluate the benefits of adaptive trial spacing.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Existing diagnosis of chronic (\>6 months) aphasia subsequent to left hemisphere stroke.
* Impaired performance on 2/8 sections of the Comprehensive Aphasia Test.
* Must have access to a high-speed internet connection and be able to participate in telehealth.
Exclusion Criter…
Inclusion Criteria:
* Existing diagnosis of chronic (\>6 months) aphasia subsequent to left hemisphere stroke.
* Impaired performance on 2/8 sections of the Comprehensive Aphasia Test.
* Must have access to a high-speed internet connection and be able to participate in telehealth.
Exclusion Criteria:
* History of other acquired or progressive neurological disease.
* Significant language comprehension impairments
* Unmanaged drug / alcohol dependence.
* Severe diagnosed mood or behavioral disorders that require specialize mental health interventions.
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