Imaging the Pathogenesis of Cerebral Small Vessel Disease
Recruiting
Observational Study
Ischemic Stroke
Hypertension
Hyperlipidemias
Diabetes
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 50 (estimated)
- Sponsor
- Johns Hopkins University · Other
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About This Trial
Cerebral small vessel disease (CSVD) can lead to vascular cognitive impairment and dementia (VCID). The hallmark of CSVD is the appearance and progression of white matter hyperintensities (WMH) on MRI. The goal of this study it to recruit and follow individuals at risk for WMH progression and use serial MRI scanning to gain insights into the pathogenesis of CSVD.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Clinical or radiographic evidence of ischemic stroke
* One vascular risk factor (hypertension, hyperlipidemia, or diabetes)
* Evidence of cerebral small vessel disease on MRI
Exclusion Criteria:
* Inability to complete 3 research MRI scans over 1.25 years
Contacts