No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Supportive Care
Participants needed
45 (estimated)
Sponsor
University of Alabama at Birmingham · Other
Who this trial is looking for
This trial is looking for patients who are scheduled for knee or hip replacement surgery and currently take opioids for pain. Participants will meet with a pharmacist to get help reducing their opioid dose before surgery.
Are You a Good Fit for This Trial?
Must not be takingBuprenorphineMethadoneLong-acting opioidsFentanyl patches
You may be able to join if
I am scheduled for knee or hip replacement surgery in 4-8 weeks.
I take between 20 and 90 MME of oral opioids and have been on this dose for at least 3 months.
I have a reliable phone number to be contacted.
I speak English.
You may not be able to join if
I take buprenorphine.
I take methadone.
I take long-acting opioids like extended-release oxycodone.
I use fentanyl patches.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The goal of this clinical trial is to develop an pharmacist-led preoperative opioid taper intervention for patients undergoing total knee or hip replacement who are on chronic opioids before their surgery. The main questions it aims to answer are:
* Is the intervention feasible and acceptable to patients?
* Does the intervention result in a decrease in opioid dose during the preoperative period?
…
The goal of this clinical trial is to develop an pharmacist-led preoperative opioid taper intervention for patients undergoing total knee or hip replacement who are on chronic opioids before their surgery. The main questions it aims to answer are:
* Is the intervention feasible and acceptable to patients?
* Does the intervention result in a decrease in opioid dose during the preoperative period?
Participants will meet with a clinical pharmacist, who will provide some basic education on pain and opioids, and will propose an opioid taper schedule. The pharmacist will then follow-up with the participant by phone each week until surgery to assess progress and adjust the taper as necessary.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* decided to pursue primary, unilateral total knee or hip arthroplasty with planned surgery date in 4-8 weeks
* currently taking between 20 and 90 MME of oral opioids, and that dose has been stable for at least 3 months
* have a reliable telephone number for contact
* speaks Eng…
Inclusion Criteria:
* decided to pursue primary, unilateral total knee or hip arthroplasty with planned surgery date in 4-8 weeks
* currently taking between 20 and 90 MME of oral opioids, and that dose has been stable for at least 3 months
* have a reliable telephone number for contact
* speaks English
Exclusion Criteria:
* Taking opioid medications that include:
* Buprenorphine
* Methadone
* Long-acting formulations of opioid pain medications (e.g., extended-release oxycodone and extended-release morphine)
* Transdermal formations of opioid pain medications (e.g., fentanyl patches)
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