Placebo Effects in Stroke Recovery

Mechanisms of Open and Hidden Placebo in Stroke Recovery

Recruiting N/A Interventional Study
Stroke Hemiparesis
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Other
Participants needed
56 (estimated)
Sponsor
Spaulding Rehabilitation Hospital · Other
Who this trial is looking for

This trial is looking for adults with weakness on one side of their body due to a stroke that happened at least 6 months ago. Participants will help researchers understand how placebos might help in recovery.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have weakness on one side of my body due to a chronic stroke.
  • My stroke occurred at least 6 months ago.
  • I have a motor assessment score between 12 and 56.
  • Before my stroke, I had a low level of disability.
  • I am 18 years old or older.

You may not be able to join if

  • I have a specific type of stroke that affects the front part of my brain.
  • I can't understand instructions.
  • I have a medical device like a cochlear implant.
  • I have unstable medical conditions.
  • I have a high score on a depression rating scale.
  • I have pain in my joints or affected arm that could affect the study.
  • I am pregnant.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

This trial aims to investigate whether placebo in isolation (open and hidden) has a specific neural signature in stroke subjects thus providing a novel mechanism to explain placebo effects that can be used to ultimately enhance stroke rehabilitation therapies.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Adults with hemiparesis due to chronic stroke 2. Stroke duration of 6 months or more 3. Fugl-Meyer scale upper extremity motor assessment score of \> 11 and ≤ 56 4. Pre-stroke disability (defined as a score of \< 3 on the Modified Rankin Scale) 5. Age 18 or older Exclusion C…
Contacts

Felipe Fregni, MD, PhD, MPH

6179526156

fregni.felipe@mgh.harvard.edu

CONTACT

Elly Pichardo, MD

6179526154

epichardo@partners.org

CONTACT