No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 99
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
70 (estimated)
Sponsor
Johns Hopkins University · Other
Who this trial is looking for
This trial is looking for adults who have had a stroke and have difficulty speaking. Participants will try two different types of language therapy to see which one helps improve their communication skills.
Are You a Good Fit for This Trial?
You may be able to join if
I am 18 years old or older.
I have a good understanding of English.
I have had a left-sided stroke within the last 1-4 months or more than 6 months ago.
I have been diagnosed with aphasia caused by my stroke.
I can give my consent or have someone who can.
You may not be able to join if
I have a history of brain disease other than stroke.
I have a serious mental illness or developmental disorder.
I cannot follow the treatment procedures as required.
I have severe vision or hearing loss.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The investigators propose a pilot crossover trial of 2 behavioral language treatments, with randomized order of treatments and blinded assessors, to determine if a therapy designed to stimulate right hemisphere functions (Producing Increasingly Complex Themes Using Right-hemisphere Engagement Implemented with Telemedicine - PICTURE IT; described below) is more effective in improving discourse than…
The investigators propose a pilot crossover trial of 2 behavioral language treatments, with randomized order of treatments and blinded assessors, to determine if a therapy designed to stimulate right hemisphere functions (Producing Increasingly Complex Themes Using Right-hemisphere Engagement Implemented with Telemedicine - PICTURE IT; described below) is more effective in improving discourse than a published computer delivered lexical treatment (shown previously to improve naming) in subacute post-stroke aphasia.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age 18 or older
2. Premorbid proficiency in English
3. Left hemisphere ischemic or hemorrhagic stroke confirmed by imaging, which occurred either 1-4 months or ≥ 6 months ago
4. Diagnosis of aphasia secondary to stroke as defined using the Western Aphasia Battery-Revised Apha…
Inclusion Criteria:
1. Age 18 or older
2. Premorbid proficiency in English
3. Left hemisphere ischemic or hemorrhagic stroke confirmed by imaging, which occurred either 1-4 months or ≥ 6 months ago
4. Diagnosis of aphasia secondary to stroke as defined using the Western Aphasia Battery-Revised Aphasia Quotient \< 93.8.
5. Capable of giving informed consent or indicating another to provide informed consent
Exclusion Criteria:
1. Prior history of neurologic disease affecting the brain (e.g., brain tumor, multiple sclerosis, traumatic brain injury) other than stroke
2. Prior history of severe psychiatric illness, developmental disorders or intellectual disability (e.g., PTSD, schizophrenia, obsessive-compulsive disorder, autism spectrum disorders)
3. Inability to follow the treatment procedure as indicated by appropriate (not necessarily accurate) engagement during 5 probes of each.
4. Uncorrected severe visual loss or hearing loss by self-report and medical records
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