Tau Networks in Psychotic Alzheimer's Disease
Recruiting
Observational Study
Alzheimer Disease
Alzheimer Disease With Delusions
Alzheimer Disease With Psychosis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 65 – 85
- Sex
- Any
- Study type
- Observational
- Participants needed
- 91 (estimated)
- Sponsor
- Northwell Health · Other
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About This Trial
This research project aims to understand the brain mechanisms behind the manifestation of psychotic symptoms in Alzheimer´s disease (AD), and nature of the unique relationship with tau pathology. Amongst the cognitive manifestations of psychosis are impairments related to frontal circuits (social cognition, working memory and executive function deficits). The investigator's previous work suggests …
Trial Locations
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Eligibility Criteria
Inclusion Criteria Alzheimer´s disease (AD) participants:
* Age 65-85 years old.
* Diagnosis of probable AD dementia according to National Institute on Aging-Alzheimer's Association (NIA-AA) criteria.
* Mini-Mental State Examination (MMSE) score ≥ 10 and ≤ 26 at the screening visit.
* Clinical Deme…
Contacts