Smell Training for Long COVID Smell Loss
Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID)
Recruiting
Phase 2
Phase 3
Interventional Study
Smell Dysfunction
Olfactory Disorder
Long COVID
Pivotal Trial
This treatment is in the last trial phase before FDA approval.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Trial phase
- Phase 2/3
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 145 (estimated)
- Sponsor
- Medical University of South Carolina · Other
Who this trial is looking for
This trial is looking for people with ongoing smell loss after COVID-19. Participants will do daily treatment at home and attend three study visits at a research center over 12 weeks.
Are You a Good Fit for This Trial?
You may be able to join if
- I have ongoing smell loss related to COVID-19
- I tested positive for COVID-19 at least a month ago
- I had a normal sense of smell before COVID-19
- I have never tried smell training or nerve stimulation
- I can understand English and give my consent
You may not be able to join if
- I have had a head injury
- I have a sinus condition
- I have a neurological disorder
- I have a serious mental illness
- I have had suicidal thoughts in the last month
- I currently smoke heavily
- I have taken oral or nasal steroids in the last month
- I am pregnant or trying to become pregnant
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Persistent smell loss that can include diminished or distorted smell function is a common symptom of long COVID syndrome. There are limited treatment options for long COVID-related smell loss. This study aims to determine the efficacy of two at-home treatments, smell training and non-invasive trigeminal nerve stimulation. This study requires participants to conduct daily at-home treatment sessions…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* treatment-seeking for COVID-related persistent SL (anosmia, hyposmia, phantosmia or parosmia)
* at least 1-month from SARS-coV-2 PCR-positive and/or rapid home-positive tests
* normal sense of smell prior to COVID
* naïve to both smell training (ST) and trigeminal nerve stimul…
Contacts