Closed-Loop Therapy for Mild Cognitive Impairment
Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease
Recruiting
N/A
Interventional Study
Alzheimer Disease
Mild Cognitive Impairment
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 50 – 80
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 70 (estimated)
- Sponsor
- Massachusetts General Hospital · Other
Who this trial is looking for
This trial is looking for people between 50 and 80 years old who have mild cognitive problems likely due to Alzheimer’s disease. Participants will take tests and may receive a non-invasive therapy while researchers study its effects.
Are You a Good Fit for This Trial?
You may be able to join if
- I have mild cognitive impairment likely due to Alzheimer's disease.
- I am between 50 and 80 years old.
- I am a native English speaker.
You may not be able to join if
- I have a brain tumor or other structural brain lesion.
- I have an ongoing serious medical condition like cancer or heart disease.
- I have a history of alcohol or substance abuse for over 10 years.
- I have conditions that would make transcranial stimulation unsafe for me.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The project is a placebo-controlled study that aims to use closed-loop transcranial alternating current stimulation (tACS) to study patients with symptoms of mild cognitive impairment which is likely due to Alzheimer's disease or another form of dementia (AD-MCI). Patients will undergo an EEG and complete some questionnaires and computer tasks during each study visit. The project has the following…
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion Criteria:
* Overall cognitive functional status consistent with amnesic MCI (CDR 0.5) likely due to AD (AD biomarker supported)
* 50-80 years of age
* English native speakers
Exclusion Criteria:
* Known presence of a structural brain lesion (e.g., tumor, cortical infarct)
* Acute or dec…
Contacts