Metformin for Improving Blood Vessel Function After Gestational Diabetes

Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes

Recruiting Early Phase 1 Interventional Study
Gestational Diabetes
Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 45
Sex
Female
Trial phase
Early Phase 1
Study type
Interventional
Purpose
Basic Science
Participants needed
30 (estimated)
Sponsor
Anna Stanhewicz, PhD · Other
Who this trial is looking for

This trial is looking for women who have had gestational diabetes and are at least 12 weeks postpartum. Participants will be given metformin to see if it helps improve blood vessel function in these women.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am at least 12 weeks postpartum
  • I had gestational diabetes
  • I had a healthy pregnancy

You may not be able to join if

  • I have been diagnosed with prediabetes or diabetes
  • I currently use tobacco
  • I have cardiovascular or metabolic disease
  • I take medication for cardiovascular or metabolic disease
  • I had high blood pressure during pregnancy
  • I am currently pregnant

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

The purpose of this investigation is to examine the mechanisms mediating vascular dysfunction in women who have had gestational diabetes and how metformin may be a valuable treatment tool to improve microvascular function in these women before the onset of disease.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * ≥12 weeks and ≤5 years postpartum * history of GDM or healthy pregnancy Exclusion Criteria: * prediabetes or diabetes (HbA1c ≥5.7%) * current tobacco use * cardiovascular or metabolic disease * cardiovascular or metabolic medication * history of hypertension during pregnancy…
Contacts

Anna Stanhewicz, PhD

3194671732

anna-stanhewicz@uiowa.edu

CONTACT