Diet and Exercise Program for Knee Osteoarthritis Prevention
The Osteoarthritis Prevention Study
Recruiting
N/A
Interventional Study
Osteoarthritis, Knee
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 50 and older
- Sex
- Female
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 1,230 (estimated)
- Sponsor
- Wake Forest University · Other
Who this trial is looking for
This trial is looking for adult women aged 50 and older who are obese but have little to no knee pain. Participants will engage in a program involving weight loss, exercise, and maintaining their weight to help prevent knee osteoarthritis.
Are You a Good Fit for This Trial?
You may be able to join if
- I am female
- I have a BMI of 30 or greater
- I have no knee osteoarthritis on x-ray or MRI
- I have little to no knee pain, less than 15 days a month
You may not be able to join if
- I have symptomatic or severe coronary artery disease
- I cannot walk without a walking device
- I am blind
- I have type 1 diabetes
- I am receiving treatment for cancer
- I have had a knee injury in the past year
- I have had a knee injection in the past 6 months
- I have a BMI of less than 30
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
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About This Trial
The goal of this study is to establish the efficacy of an intervention of dietary weight loss, exercise, and weight-loss maintenance for knee Osteoarthritis (OA) prevention in adult females aged ≥ 50 years with obesity and no or infrequent knee pain. The primary aim is to compare the effects of a dietary weight loss, exercise, and weight-loss maintenance to an attention control group in preventing…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Female
* BMI ≥ 30 kg/m2
* An eligible knee will have no OA by xray and MRI
* No or infrequent knee pain (\< 15 days/month) in the same knee
Exclusion Criteria:
* symptomatic or severe coronary artery disease
* unable to walk without a device
* blindness
* type 1 diabetes
* a…
Contacts