The Osteoarthritis Prevention Study
Recruiting
N/A
Interventional Study
Osteoarthritis, Knee
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About This Trial
The goal of this study is to establish the efficacy of an intervention of dietary weight loss, exercise, and weight-loss maintenance for knee Osteoarthritis (OA) prevention in adult females aged ≥ 50 years with obesity and no or infrequent knee pain. The primary aim is to compare the effects of a dietary weight loss, exercise, and weight-loss maintenance to an attention control group in preventing…
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Eligibility Criteria
Inclusion Criteria:
* Female
* BMI ≥ 30 kg/m2
* An eligible knee will have no OA by xray and MRI
* No or infrequent knee pain (\< 15 days/month) in the same knee
Exclusion Criteria:
* symptomatic or severe coronary artery disease
* unable to walk without a device
* blindness
* type 1 diabetes
* a…
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