Steroid Dose Reduction for Rheumatoid Arthritis

Dynamic Treatment Regiments for Glucocorticoid Tapering

Recruiting Phase 2 Interventional Study
Rheumatoid Arthritis
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Health Services Research
Participants needed
200 (estimated)
Sponsor
VA Office of Research and Development · Federal
Who this trial is looking for

This trial is looking for people with rheumatoid arthritis who want to learn more about safely lowering their steroid medication doses. Participants will take part in a study that involves making dose changes and reporting their experiences.

Are You a Good Fit for This Trial?
Must be taking Prednisone

You may be able to join if

  • I can read and speak English.
  • I am willing to follow all study procedures.
  • I have been diagnosed with rheumatoid arthritis by a medical provider.
  • I have been taking oral prednisone and another approved RA medication for the last 90 days.
  • I can take medicine by mouth.

You may not be able to join if

  • I have used glucocorticoids for more than 2 weeks in the past year for something other than rheumatoid arthritis.
  • My rheumatoid arthritis is more than moderately active.
  • I have been diagnosed with adrenal insufficiency.
  • I am pregnant.
  • I have a self-reported medical or psychiatric condition that could affect my participation.
  • I have used artificial nails or nail enhancements in the last 6 months.
  • I have any impairment or situation that would stop me from completing the study.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial
The purpose of this clinical trial is to better understand how people with rheumatoid arthritis (RA) respond to gradual dose reduction, or "tapering", of steroid medications like prednisone. Some people with RA have symptoms when steroid dose is reduced, while others don't. This trial will look at different patient characteristics, including levels of inflammation in the body, differences in the w…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: Ability to read and speak English to allow for written informed consent and patient-reported outcomes measures. * Provision of signed and dated informed consent form * Stated willingness to comply with all study procedures and availability for the duration of the study * Abilit…
Contacts

Olivia B Dickinson, BA

(734) 548-2987

Olivia.Dickinson@va.gov

CONTACT