No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
12 – 18
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
200 (estimated)
Sponsor
Children's Hospital Los Angeles · Other
Who this trial is looking for
This trial is looking for adolescents with depression who have trouble aligning their sleep schedule with their natural body clock. Participants will take part in a sleep intervention program designed to improve their mood and sleep patterns.
Are You a Good Fit for This Trial?
Rules you outTerminal end-stage cancer
You may not be able to join if
I have active psychosis.
I have Bipolar Disorder.
I have drug dependence.
I have a severe medical condition that has changed within the last month.
I have a psychiatric condition that could interfere with the study.
I currently use medications or herbs that affect my sleep.
I have changed my medication in the last 8 weeks.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The overall aim of this proposal is a confirmatory efficacy trial sufficiently powered and designed to test the hypothesis that improving the relationship between biological circadian timing and waketime, a novel modifiable target, improves depression outcomes in a subgroup of adolescents with depression and a misaligned relationship between biological circadian timing and waketime utilizing a cog…
The overall aim of this proposal is a confirmatory efficacy trial sufficiently powered and designed to test the hypothesis that improving the relationship between biological circadian timing and waketime, a novel modifiable target, improves depression outcomes in a subgroup of adolescents with depression and a misaligned relationship between biological circadian timing and waketime utilizing a cognitive-behavioral sleep intervention.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Exclusion Criteria:
* mental health/behavioral symptoms that would preclude productive engagement in study assessments or intervention (e.g., active psychosis; Bipolar Disorder; drug dependence
* severe or unstable medical or psychiatric condition such that treatment has change…
Inclusion Criteria:
Exclusion Criteria:
* mental health/behavioral symptoms that would preclude productive engagement in study assessments or intervention (e.g., active psychosis; Bipolar Disorder; drug dependence
* severe or unstable medical or psychiatric condition such that treatment has changed within the last month or is expected to change during the course of the study or that would preclude ability to adhere to study procedures (e.g. terminal end-stage cancer)
* current use of medications or herbs with known effects on sleep
* plan to undergo or have had medication change in the last 8 weeks
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