Ultra High-Resolution CT for Coronary Heart Disease
CORE-COMPARE Pilot Study
Recruiting
N/A
Interventional Study
Coronary Heart Disease (CHD)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 21 – 85
- Sex
- Any
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 140 (estimated)
- Sponsor
- Johns Hopkins University · Other
Who this trial is looking for
This trial is looking for people aged 21 to 85 with signs of coronary heart disease. Participants will help researchers understand if a new scanning technology is better at identifying this condition than standard scans.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 21 and 85 years old.
- I have a clinical history suggesting coronary heart disease.
- I have been referred by my primary cardiologist for a CT scan.
- I can understand and sign the Informed Consent Form.
- I am a woman of childbearing potential and have had a negative pregnancy test within 24 hours of the study.
You may not be able to join if
- I have a known allergy to iodinated contrast media.
- I have a history of multiple myeloma or organ transplantation.
- My serum creatinine level is above 1.5 mg/dl.
- My creatinine clearance is below 60 ml/min.
- I have atrial fibrillation or uncontrolled rapid heart rate.
- I have evidence of severe heart failure.
- I have known or suspected moderate to severe aortic stenosis.
- I have had a previous coronary intervention or bypass surgery.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The utility of Ultra High-Resolution Computed Tomography (UHR-CT) compared to conventional CT in all-comers (i.e., a generally lower-risk population) remains uncertain but is an important area of study in order to justify wider spread implementation and use of this technology, particularly in light of reports of significantly higher radiation exposure with UHR-CT, as well as longer scan times. The…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients aged 21-85 years
* Clinical history suggestive of CHD who are referred by their primary cardiologist for further evaluation via Computed tomography angiography (CTA) will be asked to participate.
* Women of child bearing potential must demonstrate a negative pregnancy…
Contacts