Azithromycin for Pediatric Critical Asthma
Azithromycin for Critical Asthma - Pediatrics
Recruiting
Phase 2
Phase 3
Interventional Study
Pediatric Asthma
Critical Illness
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Pivotal Trial
This treatment is in the last trial phase before FDA approval.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 3 – 17
- Sex
- Any
- Trial phase
- Phase 2/3
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 100 (estimated)
- Sponsor
- Johns Hopkins All Children's Hospital · Other
Who this trial is looking for
This trial is looking for children aged 3 to 17 who are in the Pediatric Intensive Care Unit (PICU) with critical asthma. Participants will be given Azithromycin to see how it affects their condition.
Are You a Good Fit for This Trial?
You may be able to join if
- I am aged 3 to 17 years
- I am in the Pediatric Intensive Care Unit (PICU)
- I have been diagnosed with critical asthma
- I am receiving continuous inhaled beta-agonist therapy
- I am receiving intravenous beta-agonist therapy
- I am receiving intravenous systemic corticosteroids
You may not be able to join if
- I have unrepaired critical congenital heart disease
- I depend on a tracheostomy at admission
- I am currently taking Azithromycin or macrolide antibiotics
- I have a history of prolonged QT syndrome or arrhythmias
- I have ongoing respiratory issues like acute chest syndrome
- I have interstitial lung disease
- I have cystic fibrosis
- I have pulmonary hypertension
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The CR-AZI Study will assess the immunomodulatory effects of Azithromycin for pediatric Critical Asthma.
Trial Locations
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Eligibility Criteria
Inclusion criteria
* Age 3-17 years
* Admission to the PICU
* Primary diagnosis of critical asthma
* Prescription for continuous inhaled beta-agonist therapy and/or intravenous (IV) beta-agonist therapy
* Prescription for intravenous systemic corticosteroids
Exclusion criteria
* Critical Congenit…
Contacts