No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
25 – 50
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
40 (estimated)
Sponsor
Auburn University · Other
Who this trial is looking for
This trial is looking for adults aged 25 to 50 who have social anxiety, experience symptoms of depression, and avoid social situations. Participants will attend four study visits over about a month, where they will complete surveys, interviews, and brain scans, along with TMS sessions.
Are You a Good Fit for This Trial?
Rules you outCurrent pregnancyBipolar DisorderSubstance use disorderPsychotic-spectrum disorderNeurological disorderHistory of seizuresMedical illnesses affecting participation
You may be able to join if
I have been diagnosed with Major Depressive Disorder or Social Anxiety Disorder.
I score above the clinical threshold for social avoidant behavior.
You may not be able to join if
I have had changes in my psychiatric medication in the past 3 months.
I have ever been diagnosed with Bipolar Disorder.
I have been diagnosed with a substance use disorder in the past 12 months.
I have a history of a psychotic-spectrum disorder like Schizophrenia.
I am pregnant or might be pregnant.
I have a medical illness that would prevent me from participating.
I have a neurological disorder that involves brain damage.
I have experienced seizures or head trauma with loss of consciousness for more than 5 minutes.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The purpose of this study is to use transcranial magnetic stimulation (TMS) to better understand the neural circuits associated with social motivation.
Participant includes four study visits each that range from 1.5 - 3.0 hours in duration over approximately a one month period. The first study visit involves answering survey questions, a clinical interview, and computer tasks. The second study vi…
The purpose of this study is to use transcranial magnetic stimulation (TMS) to better understand the neural circuits associated with social motivation.
Participant includes four study visits each that range from 1.5 - 3.0 hours in duration over approximately a one month period. The first study visit involves answering survey questions, a clinical interview, and computer tasks. The second study visit involves a magnetic resonance imaging (MRI) scan, computer tasks, and a brief TMS protocol. The second and third study visits involve a full session of TMS followed by an MRI scan and computer tasks.
Adults in the Auburn/Opelika area and surrounding areas who avoid social situations, experience symptoms of depression or social anxiety, and are between 25 years old and 50 years old are eligible to participate.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* A diagnosis of Major Depressive Disorder OR a diagnosis of Social Anxiety Disorder (assessed/confirmed at screening visit).
* Scoring above clinical threshold on a measure of social avoidant behavior (assessed/confirmed at phone screen).
Exclusion Criteria:
* Unstable psycho…
Inclusion Criteria:
* A diagnosis of Major Depressive Disorder OR a diagnosis of Social Anxiety Disorder (assessed/confirmed at screening visit).
* Scoring above clinical threshold on a measure of social avoidant behavior (assessed/confirmed at phone screen).
Exclusion Criteria:
* Unstable psychotropic medication regimen (i.e., changes in psychotropic medication or dosage in past 3 months).
* Current or lifetime diagnosis of Bipolar Disorder.
* A diagnosis of substance use disorder within past 12 months.
* A diagnosis of psychotic-spectrum disorder such as Schizophrenia.
* Pregnancy or probable pregnancy.
* Medical illness or medical treatment that would preclude or inhibit study participation.
* Neurological disorder associated with brain damage.
* History of seizures or head trauma with loss of consciousness \> 5 minutes.
* Family history of epilepsy or personal epilepsy/seizures
* Ferromagnetic implants or ferrmagnetic objects within body (e.g., pacemaker).
Contacts
No contact information available.
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