Breathing Treatment for Multiple Sclerosis Strength
Intermittent Hypoxia in Persons With Multiple Sclerosis
Recruiting
N/A
Interventional Study
Multiple Sclerosis
Multiple Sclerosis-Relapsing-Remitting
Multiple Sclerosis, Secondary Progressive
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 75
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 21 (estimated)
- Sponsor
- Shirley Ryan AbilityLab · Other
Who this trial is looking for
This trial is looking for adults with multiple sclerosis to explore a breathing treatment that involves short periods of low oxygen. Participants will have their brain activity and ankle strength measured before and after the treatment.
Are You a Good Fit for This Trial?
You may be able to join if
- I have been diagnosed with relapsing form of multiple sclerosis.
- My disability score is between 3 and 6.5.
- I have a motor function score between 2 and 4.
- I have not had a relapse in the last year.
- I am between 18 and 75 years old.
- I can safely undergo an MRI scan.
- I take dalfampridine at the same dose for at least 2 months.
You may not be able to join if
- I have active or recent lesions on my MRI scan.
- I have uncontrolled high blood pressure.
- I have a history of epilepsy.
- I have chronic obstructive pulmonary disease.
- I have uncontrolled sleep apnea.
- I am pregnant.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
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About This Trial
This study aims to understand the mechanisms of a novel intervention involving breathing short durations of low levels of oxygen for persons with multiple sclerosis (MS). This intervention with low levels of oxygen is called Acute Intermittent Hypoxia (AIH), the levels of oxygen experienced are similar to breathing the air on a tall mountain, for less than 1 minute at a time. Previous studies have…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Diagnoses of relapsing form of MS (including relapsing-remitting MS and secondary-progressive MS)
* Expanded Disability Status Scale (EDSS) score of at least 3 and no more than 6.5
* Motor Functional System Scale (FSS) between 2-4
* Relapse free for at least 1 year
* Age ≥ 18 …
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