Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 55
Sex
Female
Trial phase
Phase 4
Study type
Interventional
Purpose
Other
Participants needed
60 (estimated)
Sponsor
Malamo Countouris · Other
Who this trial is looking for
This trial is looking for individuals who have recently had preeclampsia. Participants will take low-dose aspirin and visit the clinic three times to measure blood pressure and other health markers.
Are You a Good Fit for This Trial?
You may be able to join if
I am at least 18 years old
I have been diagnosed with preeclampsia
You may not be able to join if
I have a fetal anomaly
I am pregnant with more than one baby
I had high blood pressure before my pregnancy
I am allergic to low-dose aspirin
I had diabetes before my pregnancy
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The objective of this research project is to conduct a single-site pilot trial to assess the feasibility and effect of low-dose aspirin to augment vascular recovery in the immediate postpartum period after preeclampsia through two specific aims: 1) to pilot test the feasibility of conducting a randomized controlled trial of postpartum low dose aspirin vs. placebo, and 2) to assess the effect of po…
The objective of this research project is to conduct a single-site pilot trial to assess the feasibility and effect of low-dose aspirin to augment vascular recovery in the immediate postpartum period after preeclampsia through two specific aims: 1) to pilot test the feasibility of conducting a randomized controlled trial of postpartum low dose aspirin vs. placebo, and 2) to assess the effect of postpartum aspirin on endothelial function and blood pressure. Our central hypothesis is that postpartum administration of low-dose aspirin following preeclampsia will be feasible, improve endothelial function, and lower BP at 6 months postpartum. Subjects will undergo 3 study visits involving BP measurements, blood draws, questionnaires, and/or microiontophoresis. Up to 60 adult subjects will be enrolled at Magee-Women's Hospital.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Postpartum individuals ≥18 years old
* Preeclampsia diagnosis
Exclusion Criteria:
* Fetal anomaly
* Multiple gestation
* Pre-pregnancy hypertension
* Allergy or contraindication to low-dose aspirin
* Pre-pregnancy diabetes
Inclusion Criteria:
* Postpartum individuals ≥18 years old
* Preeclampsia diagnosis
Exclusion Criteria:
* Fetal anomaly
* Multiple gestation
* Pre-pregnancy hypertension
* Allergy or contraindication to low-dose aspirin
* Pre-pregnancy diabetes
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