Thiamine for Cognitive Issues after Heart Bypass Surgery
Thiamine Intervention and Coronary Artery Bypass Grafting
- Age
- 60 – 80
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 52 (estimated)
- Sponsor
- University of California, Los Angeles · Other
This trial is looking for patients with coronary heart disease who are scheduled for bypass surgery. It focuses on understanding if thiamine can help with memory problems that sometimes occur after the surgery.
You may be able to join if
- I have coronary heart disease.
- I am scheduled for bypass grafting surgery.
- I have thiamine deficiency before the surgery.
- My EuroSCORE II is above 1.5%.
- I will have off-pump surgery.
You may not be able to join if
- I have been diagnosed with dementia.
- I currently take thiamine.
- I have a thiamine allergy.
- My blood sugar levels are uncontrolled.
- I cannot give consent due to my illness.
- I have had seizures or head trauma in the past few years.
- I have had a stroke.
- I have a psychiatric disease.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your EligibilityThe purpose of this study is to gain a better understanding of the association between brain changes and cognitive deficits in coronary heart disease (CHD) patients undergoing coronary artery bypass grafting (CABG) and whether a low-cost thiamine intervention can be used to reduce post-CABG cognitive issues in CHD subjects.
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