No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 70
Sex
Any
Trial phase
Early Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
600 (estimated)
Sponsor
University of Texas at Austin · Other
Who this trial is looking for
This trial is looking for adults with symptoms of depression. Participants will complete questionnaires, take part in eye-tracking tasks, and have interviews with researchers.
Are You a Good Fit for This Trial?
You may be able to join if
I have given my consent to participate.
I can speak and understand English.
I score 13 or more on a depression questionnaire.
I am between 18 and 70 years old.
I have not changed my antidepressant medication in the past 12 weeks.
You may not be able to join if
I have had thoughts of suicide in the past six months.
I have been diagnosed with bipolar or psychotic disorders.
I have had substance use issues in the past year.
I am currently taking opioid pain medications.
I am currently receiving psychotherapy.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The goal of this clinical trial is to compare the efficacy of two related, but different ABM (Attention Biased Modification) treatments for depression in adults with elevated symptoms of depression. The main aims are:
* Aim 1:examine whether gamified ABM leads to greater change in the primary and secondary outcomes than sham ABM
* Aim 1: establish that gamified ABM is at least as effective as tra…
The goal of this clinical trial is to compare the efficacy of two related, but different ABM (Attention Biased Modification) treatments for depression in adults with elevated symptoms of depression. The main aims are:
* Aim 1:examine whether gamified ABM leads to greater change in the primary and secondary outcomes than sham ABM
* Aim 1: establish that gamified ABM is at least as effective as traditional ABM.
* Aim 2: identify moderators of ABM efficacy and mechanisms responsible for its efficacy.
* Aim 3: Identify the durability of ABM on depression symptoms during short-term follow-up
Participants will complete self-report questionnaires, complete eye-tracking tasks, and be clinically assessed through interviews by clinician researchers.
If there is a comparison group: Researchers will compare sham, traditional, and gamified treatment groups to see if they moderate symptoms of depression.
Trial Locations
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City
State
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Status
Eligibility Criteria
Inclusion Criteria:
* Provided informed consent
* Fluent in English
* Scored 13 or greater on the QIDS-SR at the baseline assessment
* Between the ages of 18 to 70
* Have had no changes in medication and dosage in the past 12 weeks (if currently on antidepressant medication)
Exclusion Criteria:
*…
Inclusion Criteria:
* Provided informed consent
* Fluent in English
* Scored 13 or greater on the QIDS-SR at the baseline assessment
* Between the ages of 18 to 70
* Have had no changes in medication and dosage in the past 12 weeks (if currently on antidepressant medication)
Exclusion Criteria:
* Reported suicidal behavior or significant suicidal ideation within the past six months using the Columbia-Suicide Severity Rating Scale (C-SSRS)
* Met criteria for current or past bipolar or psychotic disorders
* Current (i.e., within the past 12 months) substance use disorders of moderate or greater severity on the Mini International Neuropsychiatric Interview (MINI)
* Currently taking opioid analgesics or systemic corticosteroid use as these medications
* Currently receiving psychotherapy
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