Studying Heart and Weight Loss in Obese Adults
EVOC - EVs in Obesity and Cardiometabolic Disease
Recruiting
Observational Study
Cardiovascular Diseases
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 100 (estimated)
- Sponsor
- Massachusetts General Hospital · Other
Who this trial is looking for
This trial is looking for adults who are obese and having weight loss surgery. Participating involves providing samples of fat and blood to help researchers understand how certain small particles in the body can affect heart health and diabetes.
Are You a Good Fit for This Trial?
You may be able to join if
- I am at least 18 years old
- I am obese
- I have pre-diabetes or diabetes
You may not be able to join if
- I am pregnant
- I have had a heart attack in the past
- I have heart valve disease
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The goal of this observational study is to research the impact of molecular signals from the heart, liver and fat tissue on cardiovascular disease risk, and the presentation of Type II Diabetes and diseases that affect the heart, blood vessels and metabolism (Cardiometabolic Disease). Specifically, the focus is on the content and function of Extracellular Vesicles (EVs), small sacs released from a…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age greater than or equal to 18 years of age
* Obese (BMI\>/=30 kg/m2; for obesity/bariatric surgery group)
* For 20 patients, additional criteria will be presence of pre-diabetes or diabetes (HgbA1c \> 5.7 or Fasting blood glucose \> 100).
Exclusion Criteria:
* Pregnancy (a…
Contacts