EVOC - EVs in Obesity and Cardiometabolic Disease

Recruiting Observational Study
Cardiovascular Diseases
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
100 (estimated)
Sponsor
Massachusetts General Hospital · Other
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About This Trial
The goal of this observational study is to research the impact of molecular signals from the heart, liver and fat tissue on cardiovascular disease risk, and the presentation of Type II Diabetes and diseases that affect the heart, blood vessels and metabolism (Cardiometabolic Disease). Specifically, the focus is on the content and function of Extracellular Vesicles (EVs), small sacs released from a…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age greater than or equal to 18 years of age * Obese (BMI\>/=30 kg/m2; for obesity/bariatric surgery group) * For 20 patients, additional criteria will be presence of pre-diabetes or diabetes (HgbA1c \> 5.7 or Fasting blood glucose \> 100). Exclusion Criteria: * Pregnancy (a…
Contacts

Saumya Das, MD, PhD

617-724-4500

SDAS@mgh.harvard.edu

CONTACT