Mindfulness and Heart Rate for Alzheimer’s Disease

Cardiac-Control Affecting Learning Through Mindfulness (CALM)

Recruiting N/A Interventional Study
Age-related Cognitive Decline Alzheimer Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
50 – 70
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
240 (estimated)
Sponsor
University of Southern California · Other
Who this trial is looking for

This trial is looking for people aged 50-70 to help study how mindfulness practice can affect attention and memory related to Alzheimer's disease. Participants will practice mindfulness daily for 10 weeks and provide blood and urine samples during two campus visits.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am aged between 50-70 years old
  • I speak fluent English
  • I have normal or corrected-to-normal vision and hearing
  • I have reliable access to wifi
  • I have an email account that I check regularly
  • I have a phone that receives text messages
  • I agree to provide blood and urine samples at two campus visits
  • I can devote up to 50 minutes daily to this study for 10 weeks

You may not be able to join if

  • I have a disorder that affects my breathing
  • I have cognitive impairment
  • I have regularly played Lumosity games in the past 6 months
  • I have any metal in my body that is not safe for MRI
  • I have claustrophobia
  • I have had an eye injury involving a metallic object
  • I have a cardiac pacemaker
  • I have any other implants or devices that cannot be removed for MRI

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial
Some types of meditation lead heart rate to become more steady as breathing quiets whereas others lead to large heart rate swings up and down (oscillations) as breathing becomes deeper and slower. The current study is designed to investigate how daily mindfulness practice with heart rate biofeedback during breathing in a pattern that either increases or decreases heart rate oscillation affect atte…
Trial Locations
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Eligibility Criteria
Inclusion criteria * Fluent in English * Black/African-American or White/European-American * Aged between 50-70 years old * Non-pregnant and non-menstruating (for at least the past year) * Have normal or corrected-to-normal vision and hearing * Have reliable access to wifi * Have an email account t…
Contacts

Emotion & Cognition Lab Coordinator

213-740-9543

matherlab@usc.edu

CONTACT