Exercise Program for Wheelchair Users with Multiple Sclerosis
Exercise Rehabilitation Program in MS Who Use Wheelchairs as a Primary Mobility Device
Recruiting
N/AInterventional Study
Multiple Sclerosis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
24 (estimated)
Sponsor
University of Illinois at Chicago · Other
Who this trial is looking for
This trial is looking for adults with multiple sclerosis who primarily use a wheelchair for mobility. Participants will engage in a personalized exercise rehabilitation program aimed at improving muscle strength and reducing fatigue.
Are You a Good Fit for This Trial?
You may be able to join if
I have been diagnosed with multiple sclerosis.
I am over 18 years old.
I have not had a relapse in the last 30 days.
I use a wheelchair for mobility in the community.
I can walk at least 50 feet with an assistive device.
I am at low risk for complications from physical activity.
I am willing to complete the assessments.
I am willing to undergo randomization.
You may not be able to join if
I do not have a diagnosis of multiple sclerosis.
I am under 18 years old.
I have had a relapse in the last 30 days.
I do not use a wheelchair as my primary mobility device.
I cannot walk at least 50 feet.
I am at high risk for complications from physical activity.
I am not willing to complete the testing procedures.
I am not willing to undergo randomization.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Approximately 50% of people with multiple sclerosis (MS) use a wheelchair within 30 years of the initial diagnosis. Wheelchair use in MS is often associated with fatigue as a consequence of muscle weakness. Indeed, fatigue, a prevalent consequence of MS, often becomes debilitating and exhausts energetic resources when carrying-out tasks of daily life and/or interacting with the community, as these…
Approximately 50% of people with multiple sclerosis (MS) use a wheelchair within 30 years of the initial diagnosis. Wheelchair use in MS is often associated with fatigue as a consequence of muscle weakness. Indeed, fatigue, a prevalent consequence of MS, often becomes debilitating and exhausts energetic resources when carrying-out tasks of daily life and/or interacting with the community, as these require ambulatory mobility. This experience of excessive fatigue has its roots in muscle weakness and results in reliance on a wheelchair for mobility, and the dependency on a wheelchair may further reduce muscular strength, particularly of the lower extremities. We propose that wheelchair users with MS can increase muscular strength through a personalized exercise rehabilitation, and this in turn will improve ambulatory performance and possibly reduce fatigue. To date, no research has examined the effects of this specific exercise rehabilitation program (GH method) on physical function and other disease-related outcomes in persons with MS who use wheelchairs as a primary mobility device.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* diagnosis of MS
* age above 18 years
* no relapse within last 30 days
* use of wheelchair for mobility in the community
* ability to walk at least 50 feet (or 65 steps) using an assistive device
* low risk for contraindications of physical activity indicated by no more than a …
Inclusion Criteria:
* diagnosis of MS
* age above 18 years
* no relapse within last 30 days
* use of wheelchair for mobility in the community
* ability to walk at least 50 feet (or 65 steps) using an assistive device
* low risk for contraindications of physical activity indicated by no more than a single "yes"
* response on the Physical Activity Readiness Questionnaire (PAR-Q)
* willingness to complete the assessments and undergo randomization
Exclusion Criteria:
* no diagnosis of MS
* less than 18 years of age
* not relapse-free within the last 30 days
* no use of wheelchair as primary mobility device
* no ability to walk for at least 50 feet (or 65 steps)
* high risk for contraindications based on more than a single "yes" response on the PAR-Q
* not willing to complete the testing procedures and undergo randomization
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