No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 90
Sex
Any
Study type
Interventional
Purpose
Health Services Research
Participants needed
480 (estimated)
Sponsor
Duke University · Other
Who this trial is looking for
This trial is looking for adults with Lupus to help improve how patients and doctors communicate about medications. Participants will work with healthcare providers to better understand and overcome challenges with taking their medications.
Are You a Good Fit for This Trial?
You may be able to join if
I am 18 years or older
I speak English and can give consent
I have been diagnosed with systemic lupus erythematosus
I am receiving care from doctors involved in this trial
I am prescribed at least one medication for lupus
I fill my lupus medications at a pharmacy that is linked to Surescripts
You may not be able to join if
I do not speak English
I am prescribed only corticosteroids for lupus
I have someone with me who cannot stay in the waiting room during my visit
I do not wish to be audio recorded
I am a minor without a parent or legal guardian
I am unable to give consent
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
CO-LEAD is an intervention to improve patient-provider communication and medication adherence among patients with systemic lupus erythematosus (SLE).
The purpose of this study is to optimize the culturally appropriate delivery and test the effect of the CO-LEAD intervention, which includes the following:
1. clinicians will be provided with a program to teach them to use effective communication s…
CO-LEAD is an intervention to improve patient-provider communication and medication adherence among patients with systemic lupus erythematosus (SLE).
The purpose of this study is to optimize the culturally appropriate delivery and test the effect of the CO-LEAD intervention, which includes the following:
1. clinicians will be provided with a program to teach them to use effective communication strategies with patients to review real-time pharmacy refill date, engage and formulate solutions to adherence barriers, and collaboratively overcome adherence barriers.
2. use of a reliable and valid patient-reported measure of the extent of and reasons for nonadherence that helps patients identify and communicate their adherence barriers with clinicians proactively, efficiently, and comprehensively.
Trial Locations
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City
State
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Status
Eligibility Criteria
Clinician Inclusion Criteria:
1. Adult rheumatology attendings, advanced practice providers, and fellows at the two academic institutions
2. Clinicians who have ambulatory rheumatology care at least ½ day per week
Clinician Exclusion Criteria:
1. Clinicians at Duke University who were involved in…
Clinician Inclusion Criteria:
1. Adult rheumatology attendings, advanced practice providers, and fellows at the two academic institutions
2. Clinicians who have ambulatory rheumatology care at least ½ day per week
Clinician Exclusion Criteria:
1. Clinicians at Duke University who were involved in the investigators' pilot work
2. Clinicians with an anticipated departure from the institution in the 12 months following enrollment
Patient Inclusion Criteria:
1. 18 years or older
2. English-speaking, able to provide consent
3. Diagnosed with SLE and receiving care with enrolled clinicians
4. Prescribed at least one SLE medication, and filling their SLE mediations at a pharmacy linked to Surescripts reporting visible in Epic EMR.
Patient Exclusion Criteria:
1. Non-English speakers
2. Patients who are prescribed only corticosteroids for SLE
3. Patients who are accompanied by third-party member that is not willing or able to remain in the waiting room during the patient's visit and
* Does not wish to be audio recorded
* A minor without a parental/legal guardian and/or
* Unable to give consent
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