Understanding Depression and Bipolar Disorder Treatments
Natural History of Depression, Bipolar Disorder and Suicide Risk
Recruiting
Observational Study
Behavioral Symptoms
Suicide
Self-Injurious Behavior
Sensory System Agents
Analgesics
Peripheral Nervous System Agents
Physiological Effects of Drugs
Anesthetics, Dissociative
Anesthetics, General
Anesthetics
Central Nervous System Depressants
Excitatory Amino Acid Antagonists
Excitatory Amino Acid Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Ketamine
Depression, Unipolar
Depressive Symptoms
Treatment Resistant Depression
Major Depressive Disorder
Depression, Bipolar
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 120
- Sex
- Any
- Study type
- Observational
- Participants needed
- 500 (estimated)
- Sponsor
- National Institute of Mental Health (NIMH) · NIH
Who this trial is looking for
This trial is looking for adults with depression, bipolar disorder, or suicide risk who are currently receiving treatment. Participants will answer questions and may take some additional tests to help improve treatment for these conditions.
Are You a Good Fit for This Trial?
You may be able to join if
- I am 18 years or older
- I can provide informed consent
- I can read and write in English
- I have signed consent for a related study
You may not be able to join if
- I have unstable medical conditions that affect treatment
- I am pregnant
- I have a history of substance use disorder in the last three months
- I have used illicit drugs in the last two weeks
- I use cannabis daily or cannot abstain during the study
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Mood disorders, such as depression and bipolar disorder, are difficult to treat. One reason is that there are no objective ways to measure how these disorders affect the body and respond to different treatments. In this study, researchers want to perform tests on people undergoing clinical care for mood disorders. The purpose is to understand the experience of receiving treatment for depression, b…
Trial Locations
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Eligibility Criteria
* INCLUSION CRITERIA:
In order to be eligible to participate in this study, an individual must meet all of the following criteria:
* Signed consent for Protocol 01-M-0254: The Evaluation of Patients with Mood and Anxiety Disorders and Healthy Volunteers
* Age 18 years or older
* Able to provide in…
Contacts